Dralgeen 20mg Injection

Manufacturer: Bharat Serums & Vaccines Ltd

Salt Composition : Hydralazine(20mg)


Dralgeen 20mg Injection works by relaxing and enlarging certain small blood vessels so that blood flows through them more easily. It is given under the supervision of a healthcare professional and should not be self administered. Certain patients (especially those with marked kidney damage) may require a lower dose. Blood pressure should be checked frequently. It may begin to fall within a few minutes after injection, with the average maximal decrease occurring in 10-80 minutes.


Dralgeen 20mg Injection should be used immediately after opening. It should not be added to other solutions. It may discolor upon contact with metal; discolored solutions should be discarded. Some of the common side effects of this medicine are headache, loss of appetite, nausea, vomiting, diarrhea and increased heart rate. Please contact your doctor if these side effects do not resolve or persist for a longer duration.



Basic Information

Mechanism Of Action

Dralgeen 20mg Injection is a potassium channel opener. It works by relaxing blood vessels which lowers blood pressure and allows more blood and oxygen to reach the heart and other organs.


Pharmacokinets

Pharmacokinetic data indicate hydralazine is absorbed well from the gastrointestinal tract, and has an extensive and complex metabolism depending on acetylator status: slow acetylators undergo primary oxidative metabolism, while rapid acetylators are acetylated.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dralgeen

Diarrhea

Headache

Increased heart rate

Loss of appetite

Nausea

Palpitations

Vomiting

Contra Indications

Hypersensitivity to hydralazine; coronary artery disease; mitral valvular rheumatic heart disease are contraindications for its use.

Pregnancy Related Information

Dralgeen 20mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Dralgeen 20mg Injection.


Breast Feeding Related Information

Dralgeen 20mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Indications

Hydralazine is used to treat high blood pressure (hypertension). It is also used to control high blood pressure in a mother during pregnancy (pre-eclampsia or eclampsia) or in emergency situations when blood pressure is extremely high (hypertensive crisis).

Interactions

Drug-Drug Interaction: Inform your doctor if you are taking antidepressants (clomipramine, amitriptyline), tranquilliser (diazepam), monoamine oxidase inhibitors (phenelzine, moclobemide, tranylcypromine, isocarboxazid), calcium antagonists (diltiazem, nifedipine), water tablets, nitrates, antipsychotics, female sex hormones used in contraception (oestrogens), non-steroidal anti-inflammatory drugs (NSAIDs), beta-blocker (propranolol), and medicines used to treat high blood pressure (diazoxide, minoxidil, lisinopril, captopril, enalapril).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: Avoid receiving HYDRALAZINE if you have or have ever had Systemic Lupus Erythematosus (SLE), an autoimmune condition which causes joint pain, skin rashes and fever, if you have severe tachycardia or right-sided heart failure due to increased pressure in the blood vessels of the lungs, have thyrotoxicosis (excess thyroid hormones in the blood that can cause a fast heartbeat, sweating, trembling, anxiety, increased appetite, loss of weight and intolerance of heat), myocardial insufficiency (impaired heart function) or porphyria (group of disorders due to over build-up of porphyrin in the body). If you have angina pectoris (chest pain), cerebrovascular disease (narrowing of the blood vessels in the brain), coronary artery disease, or serious liver or kidney problems, inform your doctor before receiving HYDRALAZINE.

Drug-Drug Interactions Checker List:

CLOMIPRAMINE

AMITRIPTYLINE

DIAZEPAM

PHENELZINE

MOCLOBEMIDE

TRANYLCYPROMINE

ISOCARBOXAZID

DILTIAZEM

NIFEDIPINE

OESTROGEN

PROPRANOLOL

DIAZOXIDE

MINOXIDIL

LISINOPRIL

CAPTOPRIL

ENALAPRIL

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

If you miss a dose of Dralgeen 20mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Dralgeen 20mg Injection is usually given as a slow injection into your veins by a doctor or healthcare professional.

It may cause dizziness. Do not drive or perform activities that require mental focus until you know how Dralgeen 20mg Injection affects you.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Inform your doctor about taking this medicine before undergoing any surgical procedure. 

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

FAQs

Q. What is Dralgeen 20mg Injection? What is it used for?

Dralgeen 20mg Injection belongs to a class of medicines known as potassium channel openers. It helps in the removal of potassium from the walls of arteries. This results in increased space in the arteries for the blood to flow easily, thereby reducing the workload of the heart to pump the blood. It also improves the blood and oxygen supply to your heart muscle. It is prescribed to patients with stable angina (heart-related chest pain) who cannot take other medicines (beta blockers, calcium channel antagonist) meant for the treatment of angina.

Q. How long does it take Dralgeen 20mg Injection to start working?

Dralgeen 20mg Injection starts working after about an hour of taking the medicine. However, full benefits may be seen only after 4 to 5 days. Consult your doctor if you do not notice any significant improvement in your condition.

Q. What if somebody accidentally takes an excess of Dralgeen 20mg Injection?

Taking Dralgeen 20mg Injection in excess may cause low blood pressure and the person may feel weak or dizzy. Also, one may experience irregular or fast heartbeat. In case of an overdose, immediately consult the doctor and seek emergency medical help.

Q. Can I take Dralgeen 20mg Injection if I am taking aspirin?

You should avoid taking Dralgeen 20mg Injection and aspirin together. Taking these two medicines together increases the risk of ulcer or bleeding in the mouth, stomach or intestine. Immediately consult your doctor if you notice blood in your stool or vomit while using Dralgeen 20mg Injection.