Manufacturer: Psychotropics India Ltd
Salt Composition : Drotaverine(80mg)
Drotapil 80mg Tablet can be taken with or without food, but better to take it at the same time every day for better results. The dose and how often you take it depend on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.
The most common side effects of this medicine include nausea, vomiting, and dryness in the mouth. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It may also make you feel dizzy due to low blood pressure, if that happens take precautions while driving.
Before taking this medicine, tell your doctor if you have ever had severe heart disease or have blood pressure issues, or you have liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Your doctor may check blood pressure regularly while taking this medicine.
Drotaverine is a selective inhibitor of phosphodiesterase 4 (PDE4), which is an enzyme responsible for the degradation of cyclic adenosine monophosphate (cAMP). Inhibition of PDE4 leads to elevated levels of cAMP, leading to smooth muscle relaxation.
Drotaverine is mainly eliminated via hepatic metabolism. About 67% of the drug is found in feces and 20% of the drug was eliminated with urine. Following oral administration of a single 80 mg dose, the mean half-life was 9.11 ± 1.29 hours. Following an intravenous dose of 80 mg, the mean half-life 9.33 ± 1.02 hours.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Drotapil
Nausea
Vomiting
Dryness in mouth
Vertigo
Constipation
Insomnia (difficulty in sleeping)
Hypotension (low blood pressure)
Fast heart rate
Sweating
Generally, this drug is considered safe; however, it is contraindicated in patients with severe renal, liver, and heart failure and also in children. Nausea, headaches, dizziness, arrhythmias, hypotension, and allergic reactions were also noted
Information regarding the use of Drotapil 80mg Tablet during pregnancy is not available. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Drotapil 80mg Tablet. Please consult your doctor.
Information regarding the use of Drotapil 80mg Tablet during breastfeeding is not available. Please consult your doctor.
The indications to drotaverine administration include contractions of the biliary ducts, urinary tract, and digestive smooth muscles; also dysmenorrhea and imminent abortion.
Drug-Drug Interactions: DROTAVERINE may interact with anti-Parkinson (levodopa), painkillers, anti-muscarinic drugs, and benzodiazepines. Drug-Food Interactions: No interactions found/established. Drug-Disease Interactions: Inform your doctor if you have porphyria, heart, kidney or liver problems.
Do not chew, crush or break it. Drotapil 80mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Drotapil 80mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Drotapil 80mg Tablet helps relieve pain due to smooth muscle spasms such as menstrual pain, pain due to kidney stone, and colicky pain.
Take it as per dose and duration suggested by your doctor.
It may cause a drop in your blood pressure. Monitor your blood pressure regularly and inform your doctor if you have a history of low blood pressure.
Use caution while driving or doing anything that requires concentration as Drotapil 80mg Tablet may cause dizziness.
Inform your doctor if you have severe kidney, liver, or heart disease.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Drotapil 80mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
