Duron 150mg Injection (3ml)

Manufacturer: Samarth Life Sciences Pvt Ltd

Salt Composition : Amiodarone(150mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

₹56.30

Vial of 3ml Injection

(Inclusive of all taxes)


Duron 150mg Injection is given by a slow drip (infusion) into a vein under the supervision of a doctor. Continuous monitoring of blood pressure and heart rate may be needed while this medicine is administered. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injection. If you stop taking this medicine, you may get dangerous uneven heartbeats, which can be life-threatening.

The most common side effects of this medicine include decreased blood pressure (hypotension), decreased heart rate (bradycardia), blurred vision, and application site reaction(pain, itching, and skin redness). This medicine can also cause problems with your liver, lungs, nerves, and thyroid gland. Ask your doctor what signs to look out for and report any symptoms you have. This medicine takes a long time to get cleared from the body. You may continue to have side effects after you stop using it. Ask your doctor about ways to prevent or reduce them.


Basic Information

Mechanism Of Action

Duron 150mg Injection belongs to a group of medicines called anti-arrhythmics. It works by blocking abnormal electrical signals in the heart. This helps control the uneven beating of your heart and helps it to beat normally. 

Pharmacokinets

Amiodarone is an iodine-containing compound with some structural similarity to thyroxine. The drug's high iodine content likely is a factor in its effects on the thyroid gland. The bioavailability of amiodarone is variable but generally poor, ranging from 22 to 95 percent.

Side Effects

Decreased blood pressure

Slow heart rate

Blurred vision

Application site reactions (burning, irritation, itching and redness)

Contra Indications

thyrotoxicosis

overactive thyroid gland

a condition with low thyroid hormone levels

low amount of magnesium in the blood

low amount of potassium in the blood

a painful condition that affects the nerves in the legs and arms called peripheral neuropathy

deposits on the eye

sudden blindness and pain upon moving the eye

optic neuropathy, a disease of the optic nerve

complete heart block

second degree atrioventricular heart block

torsades de pointes, a type of abnormal heart rhythm

slow heartbeat

prolonged QT interval on EKG

abnormal functioning of the sinus node of the heart

abnormal EKG with QT changes from birth

inflammation in the lungs due to an allergic reaction

a type of inflammation of the lung called interstitial pneumonitis

pneumonia with high amount of eosinophil white blood cells

damage to the liver and inflammation

liver problems

recent operation

blood circulation failure due to serious heart condition

abnormal liver function tests

pregnancy

a patient who is producing milk and breastfeeding

chronic obstructive pulmonary disease

laser surgery on cornea of eye

fainting from slow heart beat

bleeding in the alveoli of the lungs

Pregnancy Related Information

Duron 150mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

Caution is advised when consuming alcohol with Duron 150mg Injection. Please consult your doctor.


Breast Feeding Related Information

Duron 150mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

Amiodarone is a class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation. Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings.

Interactions

Bepridil.

Cisapride.

Colchicine.

Dronedarone.

Fingolimod.

Fluconazole.

Grepafloxacin.

Indinavir.

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store below 25°C

Effects Of Missed Dosage

If you miss a dose of Duron 150mg Injection, please consult your doctor.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Duron 150mg Injection may cause blurring of vision. Avoid driving or any activity requiring focus until you know how it affects you.

It makes your skin sensitive towards sunlight. Use a sunscreen and wear protective clothing while going out.

Your doctor may do regular blood tests, chest X-rays, ECG, eye test, thyroid, liver and lung function tests while you are taking this medicine.

Notify your doctor if you develop breathlessness, persistent cough, jaundice, restlessness, weight loss/gain or eye problems.

Notify your doctor about all other medicines that you are taking as Duron 150mg Injection can interact with many medicines.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

FAQs

Q. Does Duron 150mg Injection affect blood pressure?

Generally, an oral tablet of Duron 150mg Injection does not affect blood pressure. But, when given through an injection intravenously (in the vein) then it may decrease in the blood pressure. To prevent this your doctor or nurse may give Duron 150mg Injection slowly. Along with that, you may also be prescribed medicines which increase blood pressure (vasopressor agents) to the infusion.

Q. What are the warning signals of liver toxicity caused by Duron 150mg Injection?

The warning signals of liver toxicity include yellowing of the skin or eyes (jaundice), tiredness, nausea, vomiting, dark-colored urine, pale-colored stools, loss of appetite, stomach pain or high temperature. Contact your doctor immediately if you experience these symptoms.

Q. What kind of vision problems occur with Duron 150mg Injection?

You may experience blurred vision or see a circle around dazzling light (halos). It may also make your eyes dry or sensitive to light. It can even cause permanent blindness. Therefore, consult your doctor in case you experience any such problems while on Duron 150mg Injection.

Q. What does Duron 150mg Injection do to the heart?

Duron 150mg Injection blocks certain electrical signals in the heart that can cause an irregular heartbeat (arrhythmia). This way, it helps to restore normal heart rhythm and maintains a regular, steady heartbeat.