Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Desvenlafaxine(100mg), Clonazepam(0.5mg)
Strip of 10 Tablet Er
(Inclusive of all taxes)
D-Venizep 100 Tablet ER may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.
Clonazepam works by increasing levels of a calming chemical, gamma-amino-butyric-acid (GABA), in your brain. Desvenlafaxine works by increasing the levels of chemical messengers (serotonin and noradrenaline) in the brain that helps to maintain mental balance.
The pharmacokinetics of desvenlafaxine are minimally affected by food. Plasma protein binding of desvenlafaxine is low (30%) and independent of drug concentration. Studies of healthy volunteers indicate that desvenlafaxine undergoes extensive metabolism and is primarily renally excreted
Clonazepam is rapidly and completely absorbed after oral administration. The absolute bioavailability of clonazepam is about 90%. Maximum plasma concentrations of clonazepam are reached within 1 to 4 hours after oral administration. Clonazepam is approximately 85% bound to plasma proteins
Nausea
Constipation
Confusion
Insomnia (difficulty in sleeping)
Memory impairment
Headache
Ejaculation disorder
Tiredness
Erectile dysfunction
Low sexual desire
Uncoordinated body movements
Depression
a disorder with excess antidiuretic hormone called syndrome of inappropriate antidiuretic hormone.
high cholesterol.
high amount of triglyceride in the blood.
low amount of sodium in the blood.
increased risk of bleeding due to clotting disorder.
an increased risk of bleeding.
Narrow-angle Glaucoma. Clonazepam being a BZD drug is generally contraindicated in acute closed-angle glaucoma. ...
Significant Liver Disease. The liver extensively metabolizes clonazepam. ...
Hypersensitivity to Drug or Components of the Formulation.
D-Venizep 100 Tablet ER is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with D-Venizep 100 Tablet ER.
D-Venizep 100 Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
PRISTIQ, a selective serotonin and norepinephrine reuptake inhibitor (SNRI), is indicated for the treatment of major depressive disorder
Its primary indications are acute management of epilepsy and acute treatment of non-convulsive status epilepticus (complex partial seizures or absence seizures). It is also very effective in controlling the minor motor seizures of childhood, particularly petit mal absences, Lennox-Gastaut syndrome, and infantile spasm
Do not chew, crush or break it. D-Venizep 100 Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of D-Venizep 100 Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed D-Venizep 100 Tablet ER for the treatment of depression.
Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
It is also advisable to inform your doctor if you get aggressive, anxiety, trouble sleeping, an increase in activity or talking more than what is normal for you, and other unusual changes in behavior or mood.
Do not stop taking D-Venizep 100 Tablet ER unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
Inform your doctor if you are taking any other antidepressants.
If you have hypertension, monitor your blood pressure regularly while taking D-Venizep 100 Tablet ER.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
You have been prescribed D-Venizep 100 Tablet ER for the treatment of depression.
Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
It is also advisable to inform your doctor if you get aggressive, anxiety, trouble sleeping, an increase in activity or talking more than what is normal for you, and other unusual changes in behavior or mood.
Do not stop taking D-Venizep 100 Tablet ER unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
Inform your doctor if you are taking any other antidepressants.
If you have hypertension, monitor your blood pressure regularly while taking D-Venizep 100 Tablet ER.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. D-Venizep 100 Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
Q. Are there any important warnings associated with the use of D-Venizep 100 Tablet ER?
During the first few months of treatment, D-Venizep 100 Tablet ER may increase suicidal thoughts or actions in some patients. Patients having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.
Q. Can I stop taking D-Venizep 100 Tablet ER when my symptoms are relieved?
No, you should continue to take D-Venizep 100 Tablet ER even if you feel well. If you stop D-Venizep 100 Tablet ER suddenly, serious withdrawal symptoms may occur. Your doctor will probably decrease your dose gradually.
Q. How to manage weight gain associated with the use of D-Venizep 100 Tablet ER?
There are reports that suggest association of weight gain with the use of D-Venizep 100 Tablet ER. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important point to remember is that it is easier to stop weight gain than losing increased weight.
Q. Can the use of D-Venizep 100 Tablet ER cause sleepiness?
Yes, D-Venizep 100 Tablet ER can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities until you know how this medicine affects you.
Q. Can the use of D-Venizep 100 Tablet ER affect my sex life?
The use of D-Venizep 100 Tablet ER can cause sexual side effects in both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain the erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while having sex. If you experience these problems, discuss with your doctor.
Q. Can I drink alcohol while taking D-Venizep 100 Tablet ER?
No, do not drink alcohol while you are taking D-Venizep 100 Tablet ER. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by D-Venizep 100 Tablet ER.
Q. How long does D-Venizep 100 Tablet ER take to work?
Everybody responds differently to the treatment. In general, it can take several weeks to feel the full benefits of D-Venizep 100 Tablet ER, although some people may start to feel better sooner. When taking D-Venizep 100 Tablet ER, it is important to give it time to work.
Q. What are the instructions for the storage and disposal of D-Venizep 100 Tablet ER?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
