Manufacturer: Emcure Pharmaceuticals Ltd
Salt Composition : Leuprolide(45mg)
Eligard Depot 45mg Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.
Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Eligard Depot 45mg Injection reduces the amount of sex hormones (testosterone in men and estrogen in women). It works by decreasing the blood levels of testosterone in males. Eligard Depot 45mg Injection also acts by shutting off hormones made by the ovaries (female reproductive organs), so the estrogen (one of the hormones that causes females to have periods) level is lowered.
Leuprolide has a terminal elimination half-life of approximately three hours. Leuprolide administered as a 1 mg intravenous bolus in healthy males has a mean systemic clearance between 7.6 and 8.3 L/h. Leuprolide is considered extremely safe, with low dose-related toxicity and comparatively mild adverse effects.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Eligard
Decreased libido
Testicular atrophy
Increased sweating
Fatigue
Muscle weakness
Erectile dysfunction
Bone pain
Injection site reaction
Hot flashes
Contraindications to leuprolide therapy include hypersensitivity to leuprolide or any other gonadotropin-releasing hormone agonists. [13] This medication should not be used in women who are or may become pregnant. A negative pregnancy test is necessary before starting the medication.
Eligard Depot 45mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Caution is advised when consuming alcohol with Eligard Depot 45mg Injection. Please consult your doctor.
Information regarding the use of Eligard Depot 45mg Injection during breastfeeding is not available. Please consult your doctor.
Leuprolide is a medication used in the management and treatment of prostate cancer, endometriosis, uterine fibroids, precocious puberty, and other sex hormone-related conditions. It is in the GnRH agonist class of medications.
Drug-Drug Interaction: LEUPROLIDE may interact with heart rhythm problems treating drugs (quinidine, procainamide, disopyramide, amiodarone, sotalol), steroids (dexamethasone, methylprednisolone) and prednisone antibiotics (moxifloxacin), opioid pain killers (methadone) and antipsychotics (citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline).
Drug-Food Interaction: No interactions found/established.
Drug-Disease Interaction: LEUPROLIDE should be used with caution in cases of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels.
Drug-Drug Interactions Checker List:
QUINIDINE
PROCAINAMIDE
DISOPYRAMIDE
AMIODARONE
DEXAMETHASONE
METHYLPREDNISOLONE
PREDNISOLONE
MOXIFLOXACIN
METHADONE
CITALOPRAM
ESCITALOPRAM
FLUOXETINE
FLUVOXAMINE
PAROXETINE
SERTRALINE
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Eligard Depot 45mg Injection, please consult your doctor.\n
Consult a doctor before taking any medicines.
Eligard Depot 45mg Injection helps in the treatment of locally advanced or metastatic prostate cancer.
It may also be used to treat endometriosis and uterine fibroids.
It is given as an injection either under the skin or into a muscle.
It may cause dizziness and visual disturbances. Don't drive or do anything that requires mental focus until you know how it affects you.
It will cause menstrual periods to stop. Periods will resume 7-12 weeks after the final injection. Consult your doctor if you experience menstrual bleed despite treatment.
Use non-hormonal methods of contraception such as condoms to prevent pregnancy during treatment, as this medicine may be harmful to a developing baby.
Long term treatment may lead to bone loss and a higher risk of bone fractures, especially if you are a heavy drinker, a smoker, or have a family history of osteoporosis.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is Eligard Depot 45mg Injection a chemotherapy medicine?
No, Eligard Depot 45mg Injection is not a chemotherapy medicine. Eligard Depot 45mg Injection is a synthetic hormone analogue medicine which is used for the treatment of hormone-dependent conditions in men and women.
Q. Does Eligard Depot 45mg Injection stop periods?
Yes, the periods tend to stop while taking Eligard Depot 45mg Injection injections as this medicine alters the reproductive hormones in females. Sometimes, there can be vaginal bleeding in few cases. If this occurs, please contact your doctor to get yourself assessed and follow the direction of your doctor.
Q. Is Eligard Depot 45mg Injection a hormonal medicine and can it be given in pregnancy?
Yes, Eligard Depot 45mg Injection is a hormonal medicine which alters the reproductive hormones when given in females. This medication is not recommended for use in women who are or may become pregnant because this can harm the fetus in the womb. Using this medicine during pregnancy may also lead to abortion of the baby. Do inform your doctor if you are pregnant or are planning to get pregnant before starting this medication.
Q. Can taking Eligard Depot 45mg Injection affect my bones?
Yes, there are chances of Eligard Depot 45mg Injection affecting your bones. Using Eligard Depot 45mg Injection may cause a decrease in bone mineral density and make the bones weaker. In women, bone density should be assessed before starting the treatment. Special care and monitoring should be done in women with increased risk of osteoporosis. If at all needed, additional medicines may be given to prevent the development of osteoporosis in patients with decreased bone mineral density.
