Manufacturer: Samarth Life Sciences Pvt Ltd
Salt Composition : Megestrol(160mg)
Endace 160 Tablet should be taken with or without food, preferably at a fixed time each day to ensure consistent levels of medicine in the body. This medicine is not used for pregnant or breastfeeding women. It may cause side effects like high blood pressure and increased blood sugar levels but they are temporary. However, if these persist, consult with the doctor.
Endace 160 Tablet is a progestin (female hormone). It works in patients with breast cancer and endometrial cancer by affecting female hormones involved in cancer growth. It causes weight gain by increasing appetite.
The oral bioavailability of megestrol acetate is approximately 100%. After a single low oral dose of 4 mg megestrol acetate, peak serum concentrations of megestrol acetate were about 7 ng/dL (18 nmol/L) and occurred after 3 hours.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Endace
Increased appetite
Weight gain
Hot flashes
High blood pressure
Constipation
Increased glucose level in blood
Megestrol is categorized as a Category-X drug (FDA category), making it an absolute contraindication during pregnancy. Women of childbearing age should use effective birth control and notify the prescribing physician immediately if they become pregnant during treatment.
Endace 160 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
It is not known whether it is safe to consume alcohol with Endace 160 Tablet. Please consult your doctor.
Endace 160 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
indicated for the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS).
Drug-Drug Interactions: MEGESTROL may interact with a medicine used to treat heart rhythm disorders (dofetilide) and an anticoagulant (warfarin).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: MEGESTROL should be used with caution in patients with severe liver problems, a history of thrombophlebitis (blood clots), stroke, adrenal gland disorder, and diabetes.
Drug-Drug Interactions Checker List:
DOFETILIDE
WARFARIN
Do not chew, crush or break it. Endace 160 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
Consult a doctor before taking any medicines.
Consult a doctor before taking any medicines.
Endace 160 Tablet is used to treat women with certain hormone-dependent cancers such as breast cancer and endometrial cancer.
It may also be used for treating appetite and weight loss in people with advanced cancer or AIDS.
You may have to take it for atleast 2 months before you notice any changes in your appetite.
Your doctor might do regular blood tests to check your hormones and blood sugar levels while you are taking this medicine.
Do not take Endace 160 Tablet if you are pregnant or breastfeeding.
Inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision. These could be symptoms of a blood clot in a vein.
Do not stop taking the medicine suddenly without talking to your doctor first.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Endace 160 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What is Endace 160 Tablet and what is it used for?
Endace 160 Tablet contains a medicine called Megestrol which is similar to the hormone progesterone, that naturally occurs in your body. It is used in hormone-dependent cancers of breast and endometrium (lining of the uterus). It may also be used to promote appetite and weight gain in AIDS patients.
Q. Does Endace 160 Tablet make you gain weight?
Yes, Endace 160 Tablet may cause weight gain as a very common side effect. Weight gain could be due to an increase in appetite which leads to an overall increase in fat and body cell mass. Consult your doctor if you experience excessive weight gain. It is commonly used to treat malnutrition, loss of appetite and severe weight loss in patients with acquired immunodeficiency syndrome (AIDS). However, it is not intended for preventive use to avoid weight loss.
Q. When should I take Endace 160 Tablet?
You can take Endace 160 Tablet at any time of the day. However, you should take it exactly as prescribed by your doctor. Swallow it whole with a glass of water. It can be taken with or without food, preferably at the same time each day since this helps you to remember taking it. Check with your doctor if you are not sure.
Q. Does Endace 160 Tablet stop periods?
No, Endace 160 Tablet does not stop periods. However, it may interfere with your normal menstrual cycle. It may cause break-through bleeding and therefore has limited use in HIV infected women. Consult your doctor in case you experience breakthrough bleeding during the treatment with Endace 160 Tablet.
