Manufacturer: Cipla Ltd
Salt Composition : Ambrisentan(5mg)
Endobloc 5 Tablet may be taken with or without food but, it is better to take it in a dose and duration as advised by the doctor. In case, you have missed any dose than it is better to take another one as soon as you remember it.
The most common side effects of this medicine are peripheral edema, nasal congestion, sinusitis, and flushing. Let your doctor know if any of these side effects bothers you or persists for a longer duration. Dizziness may also occur in some people, so do not drive or do anything that requires mental focus if you experience such symptom.
Before receiving the treatment, inform your doctor if you are on any medication for any other health condition. Patients with liver or kidney disease must be cautious while receiving the prescription, and they must receive regular follow-ups as per the doctor’s advice.
Endobloc 5 Tablet is an endothelin receptor blocker. It blocks the action of endothelin (a natural substance) that causes blood vessels to narrow (constrict). This narrowing increases the pressure in the blood vessels of the lungs. Endobloc 5 Tablet helps relax these blood vessels and increases the supply of blood to the lungs.
Ambrisentan has a terminal half-life of 15 hours. It is thought that steady state is achieved after around 4 days of repeat-dosing. The mean oral clearance of ambrisentan was found to be 38 mL/min in healthy subjects and 19 mL/min in patients with pulmonary artery hypertension.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Endobloc
Peripheral edema
Nasal congestion (stuffy nose)
Sinus inflammation
Flushing (sense of warmth in the face, ears, neck and trunk)
Check with your doctor right away if you start to have nausea, vomiting, fever, dark urine or pale stools, a loss of appetite, stomach pain, or yellow eyes or skin. These could be signs of liver injury. This medicine may decrease the amount of sperm men make, which may affect their ability to have children.
Endobloc 5 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
It is not known whether it is safe to consume alcohol with Endobloc 5 Tablet. Please consult your doctor.
Information regarding the use of Endobloc 5 Tablet during breastfeeding is not available. Please consult your doctor.
Ambrisentan is indicated for treatment of idiopathic ('primary') pulmonary arterial hypertension (IPAH) and pulmonary arterial hypertension (PAH) associated with connective tissue disease in patients with WHO functional class II or III symptoms.
The therapeutic efficacy of Ambrisentan can be decreased when used in combination with Antrafenine. The serum concentration of Ambrisentan can be decreased when it is combined with Apalutamide. The serum concentration of Apixaban can be increased when it is combined with Ambrisentan.
Store below 30°C
If you miss a dose of Endobloc 5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
Consult a doctor before taking any medicines.
Your doctor has prescribed Endobloc 5 Tablet to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
It helps improve your quality of life, exercising ability, and delay disease progression.
Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver.
Do not drive or do anything requiring concentration until you know how Endobloc 5 Tablet affects you.
Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
Females with reproductive potential should use a reliable form of birth control while using and 1 month after stopping Endobloc 5 Tablet as it is toxic to an unborn baby.
Inform your doctor if you notice weight gain, swelling of your arms and legs, or difficulty breathing.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Endobloc 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Can Endobloc 5 Tablet cause liver problems?
Yes, Endobloc 5 Tablet commonly causes an increase in liver enzymes. It may rarely cause liver injury and inflammation of the liver because of the body’s own defences (autoimmune hepatitis). Consult your doctor if you have nausea, vomiting, loss of appetite, dark-colored urine and yellowing of the skin.
Q. How should Endobloc 5 Tablet be taken?
Usually, the doctors advise to take one dose of Endobloc 5 Tablet. You can take it with or without food but prefer taking it at the same time each day. Swallow it whole with a glass of water. Do not crush, chew or break it into pieces.
Q. Can I stop taking Endobloc 5 Tablet on my own?
No, you should not stop taking Endobloc 5 Tablet without consulting your doctor as this may worsen your condition. Talk to your doctor if you need to stop it.
Q. What is the most important thing that I should know about Endobloc 5 Tablet?
Endobloc 5 Tablet may cause serious birth defects if taken during pregnancy. Therefore, every woman who is capable of becoming pregnant should get a pregnancy test done before starting Endobloc 5 Tablet. Additionally, during treatment with Endobloc 5 Tablet you should use two reliable methods of contraception to ensure that you do not get pregnant.
