Manufacturer: Winmark Pharmaceuticals Pvt Ltd
Salt Composition : Trypsin(96mg), Bromelain(180mg), Rutoside(200mg), Diclofenac(50mg), Papain(120mg)
Enzowin-D Softgel Capsule is a pain relieving medicine. It is used to treat pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.
Enzowin-D Softgel Capsule can be taken with or without food. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.
The most common side effects of this medicine include diarrhea, nausea, indigestion, loss of appetite, stomach pain, and heartburn. If any of these side effects bother you or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.
Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.
Function. In the duodenum, trypsin catalyzes the hydrolysis of peptide bonds, breaking down proteins into smaller peptides. The peptide products are then further hydrolyzed into amino acids via other proteases, rendering them available for absorption into the blood stream. Bromelain influences blood coagulation by increasing the serum fibrinolytic ability and by inhibiting the synthesis of fibrin, a protein involved in blood clotting. In rats, the reduction of serum fibrinogen level by bromelain is dose dependent Rutoside is a natural flavone derivative. It has anti- inflammatory, anti-allergy and immunomodulating activity 20. Rutoside inhibits platelet aggregation, as well as decreasing capillary permeability, making the blood thinner and improving circulation. Rutin also strengthens the capillaries
Depending on the surface area and depth of the wound, bromelain blood serum concentrations of no more than 40 µg/ml are expected, with peak concentrations reached after 2 to 4 hours. The terminal half-life varied between 8.5 and 19.9 hours in studies. The area under the plasma concentration-time curve (AUC) of diclofenac is proportional to the dose for oral doses between 25 to 150 mg. Substantial concentrations of drug are attained in synovial fluid, which is the proposed site of action for NSAIDs. Trypsin:chymotrypsin is a widely used oral proteolytic enzyme combination to hasten repair of traumatic, surgical, and orthopedic injuries. It shows high bioavailability without losing its biological activities as an anti-inflammatory, anti-edematous, fibrinolytic, antioxidant, and anti-infective agent Of these, rutin, also known as vitamin P or rutoside, has been explored for a number of pharmacological effects. Tea leaves, apples, and many more possess rutin as one of the active constituents. Today, rutin has been observed for its nutraceutical effect
Nausea
Vomiting
Heartburn
Indigestion
Diarrhea
Loss of appetite
Stomach pain
People with allergies to pineapples should avoid bromelain. Allergic reactions may also occur in people with allergies to latex, carrot, celery, fennel, rye, wheat, papain, bee venom, or grass, birch, or cypress pollens meningitis not due to an infection. systemic mastocytosis. dehydration. hepatic porphyria. anemia. increased risk of bleeding due to clotting disorder. alcoholism. fluid accumulation in your knees. If you have problems with your liver or kidney. If you have a condition of increased eye pressure. If you have ulcers in the stomach and intestine characterized by stomach pain, acidity, nausea, vomiting, food back up, bleeding and blood in stool.A
Information regarding the use of Enzowin-D Softgel Capsule during pregnancy is not available. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Enzowin-D Softgel Capsule. Please consult your doctor.
Information regarding the use of Enzowin-D Softgel Capsule during breastfeeding is not available. Please consult your doctor.
Bromelain is promoted as a dietary supplement for reducing pain and swelling, especially of the nose and sinuses, gums, and other body parts after surgery or injury. It is also promoted for osteoarthritis, cancer, digestive problems, and muscle soreness. Topical bromelain is promoted for burns. Diclofenac is indicated for treatment of primary dysmenorrhea, for relief of mild to moderate pain, for relief of the signs and symptoms of osteoarthritis, for relief of the signs and symptoms of rheumatoid arthritis, for relief of symptoms of ankylosing spondylitis and for relief of acute migraine symptoms Rutin plays a significant role in treating edema, small blood vessel disease, varicose veins (enlarged veins), venous insufficiency, venous hypertension, superficial vein thrombosis, mouth ulcers associated with cancer treatments, and hemorrhoids TRYPSIN CHYMOTRYPSIN belongs to the group of medicines called proteolytic enzymes. The drug helps to relieve severe pain and swelling in postoperative wounds and other inflammatory diseases. Mainly the medication is used for the treatment of pain and inflammation. In few cases, it may be prescribed for digestive aid.
antiseizure medications, such as phenytoin (Dilantin) and valproic acid barbiturates. benzodiazepines, such as alprazolam (Xanax) and diazepam (Valium) asthma. fluid retention. GI toxicity. rash. renal toxicities. thrombosis. porphyria. anemia. Administration of the trypsin-chymotrypsin combination (intramuscularly) has been found to increase the levels of orally administered semi-synthetic penicillin antibiotics in the blood serum and organs of rats. Chymotrypsin is known to interact with chloramphenicol.
Swallow it as a whole. Do not chew, crush or break it. Enzowin-D Softgel Capsule may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Enzowin-D Softgel Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
You have been prescribed this combination medicine for relieving pain and inflammation in various conditions.
It is better to take this medicine with food to avoid getting an upset stomach.
Do not take it with any other pain medicine without asking your doctor first.
It may increase the severity of your condition at the start of treatment. Continue using it as prescribed by your doctor.
Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Enzowin-D Softgel Capsule may be taken with or without food, but it is better to take it at a fixed time.