Manufacturer: Lupin Ltd
Salt Composition : Salmeterol(50mcg), Fluticasone Propionate(250mcg)
Your doctor will tell you how often you need to use your inhaler. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it’s doing its job. If you stop taking it your asthma and chronic obstructive pulmonary disorder (COPD) may get worse. It should not be used to relieve sudden asthma attacks. If an asthma attack occurs, use your quick-relief inhaler (reliever). To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it does not work as well.
The most common side effects are nausea, vomiting, respiratory tract infection, fungal infections in the mouth, headache, hoarseness of voice, sore throat, cough, musculoskeletal (bone, muscle, or joint) pain, and increased heart rate. If you get there, do not stop taking it but do talk to your doctor. You can help prevent some of these symptoms by rinsing your mouth and throat with water or brushing your teeth after using your inhaler. There are other, rarer side effects that can be serious. Talk to your doctor if you're worried about them. In general, you should be trying to avoid situations that make your asthma worse (your triggers) and try not to smoke.
Ask your doctor whether it’s safe to take this medicine if you're pregnant or breastfeeding. Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
Esiflo 250 Transcaps is a combination of two medicines: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widens the airways. Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.
Salmeterol is an inhaled long-acting selective beta(2)-adrenoceptor agonist that is commercially available as the xinafoate (1-hydroxy-2-naphthoic acid) salt of the racemic mixture of the two optical isomers, (R)- and (S)-, of salmeterol. It acts locally in the lung through action on beta2 receptors.Systemic absorption can occur from two possible routes following inhalation, namely the gut after swallowing, and the lungs. For inhaled fluticasone propionate (FP), oral bioavailability is negligible due both to low absorption from the gastrointestinal tract and high hepatic first-pass metabolism.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Esiflo
Nausea
Vomiting
Respiratory tract infection
Fungal infection of mouth
Sore throat
Headache
Hoarseness of voice
Cough
Musculoskeletal (bone, muscle or joint) pain
Increased heart rate
Allergic to it or to any ingredients
Allergic to milk proteins
Breastfeeding
Hypersensitivity
Ischaemic heart disease
Planning to become pregnant
Pregnant
Esiflo 250 Transcaps may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Esiflo 250 Transcaps. Please consult your doctor.
Esiflo 250 Transcaps is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
Fluticasone and Salmeterol is used to prevent asthma attacks and to treat chronic obstructive pulmonary disease (COPD). It is not used to relieve an asthma attack that has already started. For relief of an asthma attack that has already started, you should use another medicine.
Acetaminophen
Albuterol
Amoxicillin
Amprenavir
Ascorbic acid
Boceprevir
Brimonidine
Carteolol
Cetirizine
Cholecalciferol
Check the label for directions before use. Place the capsule at the base of transhaler, not in the mouthpiece. Twist the mouthpiece completely until your hear a click and breathe in deeply through the mouthpiece. Hold your breath for up to 10 seconds. If some powder remains in the transhaler repeat the process.
Store below 30°C
If you miss a dose of Esiflo 250 Transcaps, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
This medicine is for inhalation only. The tablet should not be swallowed.
It should be taken at the same time each day.
It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
Your doctor may regularly monitor your blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Esiflo 250 Transcaps can lower blood potassium level.
Only miniscule amounts of Esiflo 250 Transcaps may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.
Trancaps must not be swallowed. Check the label for directions before use. Place the capsule at the base of transhaler, not in the mouthpiece. Twist the mouthpiece completely until your hear a click and breathe in deeply through the mouthpiece. Hold your breath for up to 10 seconds. If some powder remains in the transhaler repeat the process.
Q. What is Esiflo 250 Transcaps prescribed for?
Esiflo 250 Transcaps is prescribed to treat Chronic Obstructive Pulmonary Disease and Asthma. The symptoms may include wheezing, shortness of breath, and breathing difficulties.
Q. Can I stop taking Esiflo 250 Transcaps when my symptoms are relieved?
No, do not stop taking Esiflo 250 Transcaps. If you stop taking Esiflo 250 Transcaps, your symptoms may come back and may lead to serious complications. Take your medicine as advised by your doctor.
Q. Will Esiflo 250 Transcaps be more effective if taken in more than recommended dose?
No, taking more of this medicine will not make it more effective, rather it can lead to increased side effects. If symptoms are not getting relieved by the recommended doses, please consult the doctor for re-evaluation.
Q. What are the instructions for storage and disposal of Esiflo 250 Transcaps?
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
