Manufacturer: Glenmark Pharmaceuticals Ltd
Salt Composition : Levosulpiride(75mg), Esomeprazole(40mg)
Strip of 10 Capsule Sr
(Inclusive of all taxes)
Esoz L Capsule SR is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
Esoz L Capsule SR is a combination of two medicines: Levosulpiride and Esomeprazole. Levosulpiride is a prokinetic which works by increasing the release of acetylcholine (a chemical messenger). This increases the movement of stomach and intestines, and prevents reflux (acid going up to the food pipe).
Levosulpiride exhibited linear pharmacokinetic properties over the dose range of 25 to 100 mg by PO route and 25 to 75 mg by IM route. The corresponding mean AUC0−t increased from 449 to 1443 ng/h/mL and from 2874 to 7559 ng/h/mL, respectively.Metabolism Esomeprazole is extensively metabolized in the liver by the cytochrome P450 (CYP) enzyme system. The metabolites of esomeprazole lack antisecretory activity. The major part of esomeprazole's metabolism is dependent upon the CYP2C19 isoenzyme, which forms the hydroxy and desmethyl metabolites.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Esoz L
Nausea
Vomiting
Diarrhea
Constipation
Upset stomach
Stomach pain
Headache
Flatulence
Sleepiness
Hypersensitivity to Esoz L Capsule SR is a contraindication. In addition, Esoz L Capsule SR should not be used if you have the following conditions:
Allergic reactions
Cardiac impairment
Do not chew or crush the tablets
Epilepsy
Gastrointestinal bleeding
Hyperprolactinaemia
Hypersensitivity
Malignant mastopathy
Mammary dysplasia
Manic states
Esoz L Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Esoz L Capsule SR.
Information regarding the use of Esoz L Capsule SR during breastfeeding is not available. Please consult your doctor.
Use with caution
Below 9years: Contraindicated
Levosulpiride+Esomeprazole is used in the treatment of gastroesophageal reflux disease (acid reflux) and Peptic ulcer disease. Levosulpiride + Esomeprazole is a combination of two medicines: Levosulpiride and Esomeprazole.
If you use other drugs or over the counter products at the same time, the effects of Esoz L Capsule SR may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions.Esoz L Capsule SR may interact with the following drugs and products:
Aluminium and magnesium containing antacids
Atazanavir
Citalopram
Clomipramine
Diazepam
Imipramine
Itraconazole
Ketoconazole
Nelfinavir
Phenytoin
Do not chew, crush or break it. Esoz L Capsule SR is to be taken empty stomach.
Store below 30°C
If you miss a dose of Esoz L Capsule SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
It is a well-tolerated medicine and provides relief for a long time.
Take it one hour before the meal, preferably in the morning.
Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
Do not consume alcohol while taking Esoz L Capsule SR as it can increase the risk of stomach damage.
Long-term use may cause weak or broken bones. Take adequate intake of dietary calcium and vitamin D or their supplements. Do not take Esoz L Capsule SR for longer than prescribed.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esoz L Capsule SR is to be taken empty stomach.
Q. What are the instructions for storage and disposal of Esoz L Capsule SR?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. What is the best time to take Esoz L Capsule SR?
Take Esoz L Capsule SR exactly as directed by your doctor. It is best to take one capsule daily on an empty stomach.
Q. What are the contraindications associated with the use of Esoz L Capsule SR?
The use of Esoz L Capsule SR should be avoided in patients with known allergy to any of the components or excipients of this medicine.
Q. Can the use of Esoz L Capsule SR cause dizziness?
Yes, the use of Esoz L Capsule SR can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.
Q. Does the use of Esoz L Capsule SR lead to increased risk of fractures?
Several studies in adults suggest that treatment with Esoz L Capsule SR may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine. The risk of fracture was increased in patients who received high dose. High dose can mean multiple daily doses, and long-term therapy (a year or longer).
