Manufacturer: Fulford India Ltd
Salt Composition : Amifostine(500mg)
Ethyol 500mg Injection is given as an injection into vein (IV infusion) under the supervision of doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, decreased blood pressure, sleepiness, dizziness, and flushing are some common side effects of this medicine. Consult with your doctor if it does not go away or bothers you. It is advised to stay hydrated before taking this medicine. You will be check for blood pressure before infusion and every 5 minutes during infusion.
Before taking it, tell your doctor if you have heart diseases such as irregular heartbeat and heart failure, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.
Ethyol 500mg Injection works by removing free radical, harmful elements produced by cisplatin (a medicine used to treat cancer) or radiation therapy in tissues.
Amifostine is rapidly dephosphorylated by alkaline phosphatase in tissues primarily to the active free thiol metabolite and, subsequently, to a less active disulfide metabolite.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ethyol
Nausea
Vomiting
Decreased blood pressure
Hiccup
Sleepiness
Dizziness
Flushing (sense of warmth in the face, ears, neck and trunk)
Fever
Chills
severe or ongoing vomiting;
a light-headed feeling;
weak or shallow breathing;
chest pain, fast or slow heart rate;
a seizure; or.
redness, rash, or blisters on the palms of the hands or the soles of the feet.
Ethyol 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Ethyol 500mg Injection. Please consult your doctor.
Ethyol 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Amifostine is used protect the kidneys from harmful effects of the chemotherapy drug cisplatin in patients that receive this medication for the treatment of ovarian cancer. Amifostine is also used to decrease dryness in the mouth caused by radiation treatment after surgery for head and neck cancer.
Drug-Drug Interactions: AMIFOSTINE may have interaction with antihypertensive drugs, calcimimetic drugs (etelcalcetide),
Drug-Food Interactions: No interactions found.
Dug-Disease Interactions: Tell your doctor if you have kidney disease, heart problems, hypotension, skin disorders, or hypocalcaemia before starting the treatment.
Drug-Drug Interactions Checker List:
METOPROLOL
AMLODIPINE
ETELCALCETIDE
CILNIDIPINE
SPIRONOLACTONE
Store below 30°C
Consult a doctor before taking any medicines.
Consult a doctor before taking any medicines.
Ethyol 500mg Injection is given as an infusion into the vein ( IV infusion) under the supervision of a doctor only.
It is advisable to stay hydrated or drink plenty of fluids before taking medicine.
You will be monitored for blood pressure before and after every 5 minutes of infusion.
It may cause a decrease in calcium levels. Your doctor may monitor your calcium levels regularly and prescribe supplements if needed.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is Ethyol 500mg Injection FDA approved?
Yes, it is FDA an approved drug
Q. What is Ethyol 500mg Injection used for?
Ethyol 500mg Injection is used to reduce toxicity to kidneys associated with cisplatin therapy in patients with advanced ovarian cancer, and in prevention of dry mouth (xerostomia) during radiotherapy for head and neck cancer
Q. How does Ethyol 500mg Injection work?
It protects the normal cells against the harmful effects of chemotherapy medications and radiation treatment by producing a chemical ‘thiol' that binds to and detoxifies the harmful compounds produced by cisplatin. Ethyol 500mg Injection does not interfere with the action of cisplatin.
