Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Enoxaparin(300mg)
Evaparin Injection is injected under the skin by a doctor or nurse. It should not be injected into a muscle. The dose and length of treatment are based on your medical condition, your response to the medicine, and what you are being treated for. It may also be based on your age and weight. It is important to keep using this medicine even if you do not notice any symptoms because it is preventing future harm. If you stop taking it, you could get a blood clot. While taking this medicine you should avoid doing things that increase your risk of bleeding or injury.
The most common side effect of this medicine include bleeding, headache, increased blood platelets, and increased liver enzymes. A severe headache could be a sign of bleeding in the brain. A severe stomach ache could be a sign of bleeding in the stomach. Bleeding can be dangerous and may not be obvious. Look out for symptoms and tell your doctor if you are worried.
Before using this medicine, you should tell your doctor if you have high blood pressure, diabetes, or have had a recent stroke. You should not take it if you have any current bleeding. Some medicines should not be used with Evaparin Injection. Tell your doctor what else you are taking to make sure it is safe. If you have low body weight, you may be at increased risk of bleeding, and drinking alcohol can increase the risk of stomach bleeding.
Distribution: The apparent volume of distribution of enoxaparin estimated by anti-Factor-Xa activity is approximately 4.3 Liters. Metabolism: It is metabolized in the liver by desulfation and depolymerization to lower molecular weight fragments with reduced biologic activity.
Enoxaparin is dosed according to body weight, with 1 mg/kg every 12 hours being the most common dose used in ACS. When given intravenously, enoxaparin has a time to peak effect of 5 to 10 minutes compared with 3 to 5 hours when administered subcutaneously.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Evaparin
Bleeding
Headache
Low blood platelets
Increased liver enzymes
Known hypersensitivity to enoxaparin (urticaria, anaphylactoid reactions, anaphylaxis) or any heparin products
Active major bleeding such as gastrointestinal bleed.
History of heparin-induced thrombocytopenia within the past 100 days or presence of circulating antibodies
Evaparin Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is not known whether it is safe to consume alcohol with Evaparin Injection. Please consult your doctor.
Evaparin Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Evaparin Injection is released in small amounts in the breast milk and amounts reaching the baby are also small, which would not be expected to cause any harmful effects to the baby.
Enoxaparin is used to prevent blood clots in the leg in patients who are on bedrest or who are having hip replacement, knee replacement, or stomach surgery. It is used in combination with aspirin to prevent complications from angina (chest pain) and heart attacks.
The risk or severity of bleeding and hemorrhage can be increased when Enoxaparin is combined with Acemetacin. The risk or severity of bleeding can be increased when Enoxaparin is combined with Acenocoumarol. Acetylsalicylic acid may increase the anticoagulant activities of Enoxaparin.
Kindly do not self administer.
Store below 25°C
If you miss a dose of Evaparin Injection, please consult your doctor.
Consult a doctor before taking any medicines.
You have been prescribed Evaparin Injection for the treatment and prevention of blood clots.
Evaparin Injection increases your risk of bleeding. Be careful while shaving, using sharp objects or cutting fingernails or toenails.
Inform your doctor if you are also taking other medicines that increase the bleeding risk like aspirin and NSAIDs.
Inform your doctor if there is bleeding from gums, nose or wounds that lasts more than 15 minutes or if blood appears in your urine, stool or vomit.
Do not stop taking the medication suddenly without talking to your doctor.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How do you administer Evaparin Injection?
Evaparin Injection is a medicine which is injected beneath the skin. Fix the dose of the medicine and pinch the skin of your stomach between your finger and thumb to make a fold. After having cleaned the area, hold the syringe like a pencil and insert the full length of the needle into the skin fold. Inject the medicine and discard the syringe as instructed by your prescribing physician. Follow the instructions given by the healthcare provider strictly. Contact your doctor in case of any doubt or any reactions associated with the medicine.
Q. What are the conditions where I should be cautious before taking Evaparin Injection?
You must give a proper history to your doctor before you start taking Evaparin Injection. Inform your doctor if you have a heart valve fitted or have gastric ulcer, high blood pressure, diabetes, or kidney problems. You should also let your doctor know if you ever had a reaction to heparin or had a recent stroke, brain or spinal surgery. The chances of side effects and complications increase in presence of these conditions. Consult with your doctor and follow the instructions strictly.
Q. How to store Evaparin Injection injections?
Store Evaparin Injection injections at 25°C and do not freeze them. The multiple-dose vials should not be stored for more than 28 days after the first use. Discard the injection if you notice any particulate matter or abnormal color in the solution or any damage in the syringe. Read the medicine package leaflet before using this medication and ask the pharmacist in case of any doubt.
Q. Can Evaparin Injection be used in heart attack?
Yes, Evaparin Injection is used in the treatment of chest pain and heart attack once the standard treatment has been provided to the patient. It is given along with another blood thinner like aspirin. Being a blood-thinning agent, it prevents the blood from clotting and prevents any further episodes and complications.
