Ezycut 1.5mg Injection (20ml)

Manufacturer: Zydus Cadila

Salt Composition : Edaravone(1.5mg)


Ezycut 1.5mg Injection is administered as an injection under the supervision of a healthcare professional and should not be self-administered. It is given in cases where oral administration is not possible. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember.

The most common side effects of this medicine are headache, bruising, and walking difficulties (gait disturbance).  You may also notice some injection site reactions such as pain, redness, or swelling. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you. You should inform the doctor if you develop any allergic reactions like itching, swelling of the lips, tongue, or face, after taking the medication as these require immediate medical attention.


Basic Information

Mechanism Of Action

Ezycut 1.5mg Injection is an antioxidant. It has nootropic (enrichment of nerves) and neuroprotective properties. It works by slowing the nerve damage caused by harmful chemicals (free radicals). This delays the progression of amyotrophic lateral sclerosis (ALS) symptoms by reducing the oxidative stress (an imbalance between free radicals and antioxidants) in the brain.


Pharmacokinets

After oral administration in a fasted condition, edaravone was well absorbed with a time to reach Cmax of 0.3 to 0.8 hours. The Cmax and AUC of unchanged edaravone increased as the dose increased within the range of 30 to 300 mg.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ezycut

Bruise

Walking difficulties

Headache

Injection site reactions (pain, swelling, redness)

Contra Indications

If you are suffering from any of the following diseases, you should not take Edaravone unless your doctor advises you to do so -

Asthma

Drug Allergies

Pregnancy Related Information

Ezycut 1.5mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Ezycut 1.5mg Injection. Please consult your doctor.


Breast Feeding Related Information

Information regarding the use of Ezycut 1.5mg Injection during breastfeeding is not available. Please consult your doctor.


Children Related Information

Use with caution

Below 9years: Contraindicated

Indications

Edaravone injection is used to treat amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease; a condition in which the nerves that control muscle movement slowly die, causing the muscles to shrink and weaken). Edaravone injection is in a class of medications called antioxidants.

Interactions

Cefazolin

Cefotetan

Diazepam

Phenytoin

Piperacillin

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Ezycut 1.5mg Injection, please consult your doctor.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Ezycut 1.5mg Injection slows decline of physical function and helps relieve symptoms of amyotrophic lateral sclerosis (ALS) such as muscle cramps and fatigue.

It is given through a needle into a vein by your healthcare provider.

It takes about 60 minutes to receive a full dose of Ezycut 1.5mg Injection.

Wear relaxed, loose-fitting clothing and keep yourself hydrated when treated with this medicine.

Inform your doctor if you are pregnant or breastfeeding.

Inform your doctor immediately if you experience itching, swelling of the lips, tongue, or face, breathing problems or have trouble swallowing after receiving this medicine.

Inform your doctor if you have a known allergy to sulfa drugs.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. What are the side effects of Ezycut 1.5mg Injection?

The most common side effects of Ezycut 1.5mg Injection include confusion, headache, and difficulty in walking. Other uncommon side effects are skin allergy (rash and itching), breathing difficulty, chest tightness, wheezing, coughing (especially in people with asthma), and fungal infections.

Q. How is Ezycut 1.5mg Injection given?

Ezycut 1.5mg Injection injection comes as a solution (liquid) to be injected intravenously (into a vein) over 60 minutes by a health care professional in a doctor's office or medical facility. During the initial stage of treatment, Ezycut 1.5mg Injection is usually given once a day for the first 14 days of a 28-day cycle. After the first cycle, it is given once a day for the first 10 days of a 28-day cycle. Your doctor will decide how often you are to receive Ezycut 1.5mg Injection based on your body's response to this medication.

Q. Can amyotrophic lateral sclerosis (ALS) be cured by Ezycut 1.5mg Injection?

Ezycut 1.5mg Injection injection is used to treat amyotrophic lateral sclerosis (ALS). ALS is a condition in which the nerves that control muscle movement slowly die, causing the muscles to shrink and weaken. Ezycut 1.5mg Injection works by slowing the nerve damage associated with the worsening of ALS symptoms.

Q. What should I tell my doctor before taking Edaravone?

Inform your doctor or pharmacist if you are allergic to edaravone, any other medications, sodium bisulfite, or any of the ingredients in Ezycut 1.5mg Injection injection. If you are taking or planning to take any other prescription and nonprescription medications, vitamins, and nutritional supplements inform your doctor beforehand. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Tell your doctor if you have or have ever had asthma or if you are pregnant or planning to conceive, or are breastfeeding. If you become pregnant while receiving edaravone, call your doctor.

Q. Can ALS be prevented?

There are no studies to support if ALS can be prevented or not. However, one can reduce the possibility of acquiring the disease by knowing various risk factors. The risk factors associated with ALS include smoking and exposure to pesticides and insecticides. In addition to that, another report suggests that people who have served in the military can also have high risks of developing ALS.

Q. Who is more likely to get affected by ALS? Is it age or gender specific?

Caucasians and non-Hispanics are most likely to develop the disease. About 5 to 10 percent of all ALS cases are familial, which means that an individual inherits the disease from his or her parents. ALS can strike at any age, symptoms most commonly develop between the ages of 55 and 75. It is slightly more likely to develop in men than in women. However, as we age the difference between men and women disappears. Furthermore, some studies suggest that military veterans are about 1.5 to 2 times more likely to develop ALS because of toxin exposure during warfare.

Q. Why so many veterans and athletes get ALS?

Researchers have suggested that exposure to toxins during warfare, or strenuous physical activity, are possible reasons for why some veterans and athletes may be at increased risk of developing ALS.

Q. What are the early symptoms of ALS?

The early symptoms of ALS include muscle twitches in the arm, leg, shoulder, or tongue, muscle cramps, tight and stiff muscles (spasticity), muscle weakness affecting an arm, a leg, neck or diaphragm, slurred and nasal speech and difficulty in chewing or swallowing. For many individuals the first sign of ALS may appear in the hand or arm as they experience difficulty with simple tasks such as buttoning a shirt, writing, or turning a key in a lock. In other cases, symptoms initially affect one of the legs, and people experience awkwardness when walking or running or they notice that they are tripping or stumbling more often.