Fabiflu Tablet (34'S)

Manufacturer: Glenmark Pharmaceuticals Ltd

Salt Composition : Favipiravir(200mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Take Fabiflu Tablet only as per the dose and duration suggested by your doctor. Do not self-medicate. The most common side effects of this medicine include the increased uric acid levels in blood, diarrhea, decreased white blood cell count (neutrophils), and increased liver enzymes. If any of these side effects bother you, consult with your doctor.

To make sure it is safe for you, you should let your doctor know if you have severe kidney or liver disease before taking this medicine. Fabiflu Tablet is not recommended for women who are pregnant, suspected to be pregnant or breastfeeding, as it can cause harmful effects to the developing baby. Also, inform your doctor if you have a history of hypersensitivity to this drug, have abnormalities in uric acid metabolism, or have gout.



Basic Information

Mechanism Of Action

The mechanism of action of favipiravir is novel compared to existing influenza antivirals that primarily prevent entry and exit of the virus from cells.7 The active favipiravir-RTP selectively inhibits RNA polymerase and prevents replication of the viral genome.18 There are several hypotheses as to how favipiravir-RTP interacts with RNA dependent RNA polymerase (RdRp).7 Some studies have shown that when favipiravir-RTP is incorporated into a nascent RNA strand, it prevents RNA strand elongation and viral proliferation.7 Studies have also found that the presence of purine analogs can reduce favipiravir’s antiviral activity, suggesting competition between favipiravir-RTP and purine nucleosides for RdRp binding.7

Pharmacokinets

Studies from healthy Japanese volunteers showed that the maximum plasma concentration of favipiravir occurred at 2 hours after oral administration, and then decreased rapidly with a short half-life time of 2–5.5 hours. The plasma protein binding of favipiravir was 54% in humans.

Side Effects

Increased uric acid level in blood

Diarrhea

Decreased white blood cell count (neutrophils)

Increased liver enzymes

Contra Indications

Gout.

Kidney Disease.

Liver Disease.


Pregnancy Related Information

Fabiflu Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Fabiflu Tablet. Please consult your doctor.


Breast Feeding Related Information

Fabiflu Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

favipiravir was approved in Japan to treat cases of influenza that were unresponsive to conventional treatment.9 Given its efficacy at targetting several strains of influenza, it has been investigated in other countries to treat novel viruses including Ebola and most recently, COVID-19

Interactions

Favipiravir may increase the hepatotoxic activities of Acetaminophen.

The excretion of Adefovir dipivoxil can be decreased when combined with Favipiravir.

The excretion of Allopurinol can be decreased when combined with Favipiravir.


Typical Dosage

 Do not chew, crush or break it. Fabiflu Tablet may be taken with or without food, but it is better to take it at a fixed time.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Fabiflu Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines

Expert Advice

Fabiflu Tablet is used for the treatment of mild to moderate Covid-19 symptoms.

Inform your doctor if you have gout, uric acid, liver, or kidney disease.

Fabiflu Tablet should be administered with care to elderly patients by monitoring their general conditions.

Seek immediate medical attention if you see signs of allergic reactions like red or blistering rash, difficulty swallowing or breathing, swelling of the eyelids, lips, face, throat, or tongue.

Fabiflu Tablet can be taken on an empty or full stomach. However, taking it with food might reduce the possibility of nausea and vomiting.

It is advisable to use contraceptive methods while taking Fabiflu Tablet and for 7 days after the completion of the treatment.

Let your doctor know if you are pregnant or breastfeeding.

Fabiflu Tablet is used for the treatment of mild to moderate Covid-19 symptoms.

Inform your doctor if you have gout, uric acid, liver, or kidney disease.

Fabiflu Tablet should be administered with care to elderly patients by monitoring their general conditions.

Seek immediate medical attention if you see signs of allergic reactions like red or blistering rash, difficulty swallowing or breathing, swelling of the eyelids, lips, face, throat, or tongue.

Fabiflu Tablet can be taken on an empty or full stomach. However, taking it with food might reduce the possibility of nausea and vomiting.

It is advisable to use contraceptive methods while taking Fabiflu Tablet and for 7 days after the completion of the treatment.

Let your doctor know if you are pregnant or breastfeeding.


How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Fabiflu Tablet may be taken with or without food, but it is better to take it at a fixed time.


FAQs

Q. What is Fabiflu Tablet? What is it used for?

Fabiflu Tablet is a medicine that belongs to a class of medicines called antiviral medicines. Fabiflu Tablet is used for managing patients suffering from mild to moderate Covid-19 infection.

Q. When is the best time to start treatment with Fabiflu Tablet?

Fabiflu Tablet is best taken in mildly infected individuals than in those who have severe Covid-19 infection. This is because early use of antiviral medicines, such as Fabiflu Tablet, is seen to be more effective in treating Covid-19 infection. Delay in treatment only slows down the recovery process and worsens the existing symptoms such as breathing issues, cough, or fever. If left untreated, this viral infection may even lead to organ failure. Once tested positive for Covid-19, consult your doctor immediately.

Q. Who should not take Fabiflu Tablet?

Fabiflu Tablet should not be used for treating patients who are allergic to Fabiflu Tablet or any of its ingredients. Children should not be given Fabiflu Tablet. It should not be given to patients with severe kidney or liver disease too. Additionally, people who have any abnormal uric acid levels or are suffering from gout must inform their doctor before taking Fabiflu Tablet. If you are planning a baby, pregnant or breastfeeding, consult your doctor before starting treatment with Fabiflu Tablet to avoid any potential harm to your baby. Follow your doctor’s instructions carefully to get maximum benefit.

Q. For how long and in what dose should Fabiflu Tablet be taken?

Fabiflu Tablet should be taken in the dose and duration advised by the doctor. It is taken orally (by mouth) and the recommended dose is 1,800 mg twice on day 1, followed by 800 mg twice daily up to day 14. Do not self medicate. Follow your doctor’s instructions carefully to get maximum benefit from Fabiflu Tablet.