Manufacturer: Samarth Life Sciences Pvt Ltd
Salt Composition : Phenoxybenzamine(50mg)
Fenoxene 50mg Injection is given by or under the supervision of a doctor. You should take it in the dose and duration as advised by the doctor. It is important to take it even if you feel well or if your blood pressure is controlled. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. Your doctor will decide the time period till which you need to take this medicine.
Making some changes in your lifestyle will also help to lower your blood pressure. These may include regular exercise, losing weight, smoking cessation, reducing alcohol intake, and reducing the amount of salt in your diet as advised by your doctor. This medicine is tolerated well by most patients but it has few side effects also. Some patients may experience dizziness and sudden lowering of blood pressure on standing. Other side effects include nausea, vomiting, ejaculation disorder, and increased heart rate. Let your doctor know if these side effects bother you or do not go away.
Before taking this medicine, let your doctor know if you have any heart or kidney disease. Pregnant or breastfeeding mothers should also consult their doctor before taking it. Your doctor may check your kidney function, heart rate and blood pressure at regular intervals while you are taking this medicine.
Fenoxene 50mg Injection is an alpha blocker which helps reduce blood pressure in pheochromocytoma (a tumour of the adrenal gland). It works by opposing the action of certain hormones released from the tumor that cause the blood vessels to narrow and raise blood pressure.
Phenoxybenzamine is a nonselective α-adrenergic receptor antagonist used in patients with pheochromocytoma or paraganglionoma. The drug blunts the effects of catecholamines released from the tumor and is usually administered preoperatively in preparation for pheochromocytoma resection.
it has few side effects also. Some patients may experience dizziness and sudden lowering of blood pressure on standing. Other side effects include nausea, vomiting, ejaculation disorder, and increased heart rate. Let your doctor know if these side effects bother you or do not go away.
Concurrent administration with compounds that stimulate both alpha- and beta-adrenergic receptors may result in extreme hypotensive response and tachycardia.
Caution with use in patients with renal impairment.
May aggravate respiratory infections symptoms by increasing congestion.
Fenoxene 50mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Fenoxene 50mg Injection may cause excessive drowsiness with alcohol.
Fenoxene 50mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Phenoxybenzamine is a medication used in the management and treatment of paroxysmal hypertension and sweating resulting from pheochromocytoma. It is in the nonselective, irreversible antagonist of the alpha-adrenergic receptors class of drugs.
Drug-Drug Interaction: PHENOXYBENZAMINE may interact with calcium channel blockers (amlodipine), beta-blockers (bisoprolol, atenolol) and Angiotensin-converting enzyme (ACE) inhibitors (enalapril, captopril).
Drug-Food Interaction: PHENOXYBENZAMINE may interact with alcohol. Therefore, avoid alcohol consumption with PHENOXYBENZAMINE as it may increase dizziness or fainting.
Drug-Disease Interaction: Avoid taking PHENOXYBENZAMINE if you have ever had a heart attack within the last month or stroke. If you have angina (chest pain), lung infection, heart or kidney problems, inform your doctor before taking PHENOXYBENZAMINE.
Drug-Drug Interactions Checker List:
AMLODIPINE
BISOPROLOL
ATENOLOL
ENALAPRIL
CAPTOPRIL
Kindly do not self administer.
Store below 30°C
If you miss a dose of Fenoxene 50mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Fenoxene 50mg Injection is given as a drip into a vein (intravenous infusion) under the supervision of a doctor.
Take it in addition to lifestyle modification with regular exercise, a balanced diet, and smoking cessation.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How long should Fenoxene 50mg Injection be taken?
You should take it as long as your doctor has recommended it to you. Do not stop taking it without talking to you doctor first. Long-term use of Fenoxene 50mg Injection is not recommended as cases of developing cancer have been reported. Consult your doctor before starting the treatment.
Q. Who should not use Fenoxene 50mg Injection?
Fenoxene 50mg Injection should not be given to patients who are allergic to it. Additionally, in patients with a recent history (within the last month) of stroke or heart attack, Fenoxene 50mg Injection should be avoided. Tell your doctor if any of these conditions apply to you.
Q. How does Fenoxene 50mg Injection cause tachycardia?
Fenoxene 50mg Injection belongs to alpha receptor blockers class of medicines. Alpha receptors blockade decreases resistance thereby increasing blood flow to the skin, mucosa (membrane that lines various cavities of the body), and abdominal viscera (membrane lining the abdomen). This results in lowering of blood pressure. This reduced blood pressure and increased release of chemical messenger (noradrenaline) results in reflex tachycardia.
Q. Why is Fenoxene 50mg Injection used for pheochromocytoma?
Fenoxene 50mg Injection helps in reducing the increased blood pressure caused by Pheochromocytoma. It is a tumor of the adrenal glands. It causes the release of certain substances (catecholamines) from the adrenal glands into the bloodstream in large quantities, causing high blood pressure. Fenoxene 50mg Injection works by blocking alpha receptors, thereby decreasing blood pressure.
