Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Atorvastatin(20mg), Fenofibrate(145mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Fibator Tablet can be taken with a meal or on an empty stomach. You can take it at any time of the day but try to take it at the same time each day. This will help you remember to take it. Your doctor will prescribe the right dose depending on your lipid levels and how you respond to this medicine. Most people with high cholesterol and triglyceride do not feel ill, but stopping your medicine may increase your lipid levels, making your condition worse and increasing your risk of heart disease and stroke.
It is important to have your cholesterol and triglyceride levels (lipid profile) checked regularly. This medicine is only one part of a treatment program which should also include a healthy low-fat diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to avoid foods that are high in fat.
Nausea, stomach pain, constipation, headache, flatulence (excessive gas), and muscle pain are some of the common side effects of this medicine. These are usually mild and disappear after a short time. Consult your doctor if they persist or if you notice any yellowing of your eyes, unusual bleeding or bruising, or get repeated, severe, or unexplained muscle pains. You may be advised to get your liver function tested periodically while taking this medicine.
This medicine should not be used in conditions such as liver disease (eg. abnormal blood tests for liver function, persistent yellowness of eyes, etc.). Before taking it, let your doctor know if you have any kidney-related problems or if you are pregnant, planning a pregnancy, or breastfeeding. Diabetic patients should monitor their blood sugar levels while taking this medicine, as it may lead to an increase in blood sugar levels.
It reduces low-density lipoprotein cholesterol (LDL-C), total cholesterol, triglycerides, and apolipoprotein B and increases high-density lipoprotein cholesterol (HDL-C) in adults.
Atorvastatin is rapidly absorbed after oral administration with a peak plasma concentration at 1 to 2 hours. The bioavailability is low at 14% due to extensive first-pass metabolism. Atorvastatin is highly plasma protein bound (over 98%) and has a volume of distribution of about 380 liters.
Fenofibric acid, the active metabolite of fenofibrate, has a half life of 23 hours. Fenofibrate has a half life of 19-27 hours in healthy subjects and up to 143 hours in patients with renal failure. The oral clearance of fenofibrate is 1.1L/h in young adults and 1.2L/h in the elderly.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Fibator
Nausea
Stomach pain
Constipation
Flatulence
Headache
Muscle pain
Increased liver enzymes
Increased glucose level in blood
Using fenofibrate together with atorvastatin can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. In some cases, rhabdomyolysis can cause kidney damage and even death.
Fibator Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
It is unsafe to consume alcohol with Fibator Tablet.
Fibator Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
The fixed dose combination of Atorvastatin and Fenofibrate is indicated as an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels and to increase HDL-C in patients with mixed hyperlipidemia.
Using fenofibrate together with atorvastatin can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. In some cases, rhabdomyolysis can cause kidney damage and even death.
Do not chew, crush or break it. Fibator Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Fibator Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Notify your doctor if you experience muscle symptoms (pain or weakness), particularly if accompanied with fever.
Notify your doctor if you experience stomach pain, loss of hunger, a sick feeling or dark urine.
Do not discontinue Fibator Tablet without consulting your doctor even if you feel better.
Avoid alcohol consumption (includes wine, beer, and liquor).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Fibator Tablet is to be taken with food.
Q. Can Fibator Tablet cause liver damage?
Fibator Tablet contains Atorvastatin and Fenofibrate. A very rare (1 in 10000 patient) side effect of this medicine is liver damage. Use of this medicine should be avoided in patients with underlying liver disease. Contact your doctor immediately if you notice any early signs and symptoms of liver damage. These symptoms may include fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin or eyes, or abnormal liver enzymes.
Q. Can Fibator Tablet cause muscle pain?
Yes, Fibator Tablet can cause muscle pain by injuring the muscles. Talk to your doctor as soon as possible if you experience muscle pain, weakness or muscle cramps. It can be a sign of any muscle injury caused due to Fibator Tablet.
Q. What lifestyle changes should be adopted while taking Fibator Tablet?
Making lifestyle changes can boost your health while taking Fibator Tablet. Stop smoking, as smoking increases your risk of having a heart attack and stroke. If you are overweight or obese, try to lose weight. You should maintain a healthy diet by including fruits and vegetables in your meals. Regular exercise can make your heart strong and decrease your risk of heart attack.
Q. What medicines should I avoid while taking Fibator Tablet?
The use of Fibator Tablet along with certain medicines can cause serious problems. Consult your doctor before taking any prescription or non-prescription medicine along with Fibator Tablet.
