Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Bivalirudin(250mg)
Flopace 250mg Injection is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It is given as a drip into a vein by a doctor or a nurse. You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, exercising regularly, and losing weight if you need to.
The most common side effects of this medicine are headache, low platelet level, and fever. It may also make you bleed more easily than normal, for example, having nosebleeds or bruising. You should be extra careful while shaving, cutting nails, or using sharp objects during treatment with this medicine.
This medicine may not be suitable for everyone and should be used with caution. Inform your doctor, if you have severe kidney or liver problems. Do not take this medicine if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.
Flopace 250mg Injection is an anticoagulant that prevents the formation of harmful blood clots.
Bivalirudin has a half-life of approximately 25 minutes and a response that is linearly proportional to its dosing, with coagulation parameters returning to baseline approximately 1 to 2 hours after its discontinuation in patients with normal renal function.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Flopace
Low blood platelets
Headache
Fever
Bleeding
Active of major bleeding.
Hypersensitivity to bivalirudin or its components
Flopace 250mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is unsafe to consume alcohol with Flopace 250mg Injection.
Flopace 250mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Acute myocardial infarction, an adjunct to thrombolytic therapy.
Acute myocardial infarction - percutaneous coronary intervention - thrombosis; prophylaxis.
Deep venous thrombosis; prophylaxis.
Heparin-induced thrombocytopenia with thrombosis - heart surgery - thromboembolic disorder; prophylaxis.
Drug-Drug Interactions: BIVALIRUDIN may interact with pain killers (ibuprofen, celecoxib, hydrocodone, tramadol), blood thinners (clopidogrel, dalteparin, enoxaparin, rivaroxaban, prasugrel), and drug used to prevent heart attack or stroke (ticagrelor).
Drug-Food Interactions: Avoid smoking and alcohol consumption.
Drug-Disease Interactions: Inform your doctor if you have bleeding problems, coronary and cerebral vascular disease, or liver or kidney disease.
Drug-Drug Interactions Checker List:
IBUPROFEN
CELECOXIB
TRAMADOL
CLOPIDOGREL
ENOXAPARIN
PRASUGREL
TICAGRELOR
Store below 30°C
Consult a doctor before taking any medicines.
Consult a doctor before taking any medicines.
It is a hospital only medicine. It is given by your nurse or doctor as an infusion (drip) into a vein.
Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
Inform your doctor if you are taking other blood thinners or medicines to prevent blood clots.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Does Flopace 250mg Injection affect the liver?
Unlike other anticoagulants, Flopace 250mg Injection usually does not affect the functioning of the liver. But long-term use of Flopace 250mg Injection may increase the chances of mild liver injury in patients with elevated liver enzymes. However, the overall chances of developing any such problem are lower than other anticoagulants. It is advised that you inform your doctor if you have a history of liver disease before starting this medicine.
Q. Can I drink alcohol with Flopace 250mg Injection?
Taking alcohol while taking Flopace 250mg Injection can increase the blood-thinning effect of this medicine, thereby increasing the chance of bleeding. Regular intake of alcohol can lead to a gastric ulcer which might again cause bleeding. So, it is better to avoid alcohol while you are taking this medicine. Do consult your doctor if any such episode of bleeding occurs.
Q. How should I store Flopace 250mg Injection?
Flopace 250mg Injection should be stored at room temperature between 20º-25º C (68º-77°F) in the original carton it came in. Do not freeze. Store the medicine at a dry place and protect the medicine from moisture and light.
Q. When will I feel better after taking Flopace 250mg Injection?
Flopace 250mg Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Flopace 250mg Injection. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
