Manufacturer: Cadila Pharmaceuticals Ltd
Salt Composition : Fluorouracil(250mg)
Vial of 5ml Injection
(Inclusive of all taxes)
Florac 250mg Injection is given as injection under the supervision of doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include increased risk of infection, mouth ulcer, vomiting, weakness, and nausea. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand
Fluorouracil is a pro-drug that requires intracellular activation to exert its effects. This makes it difficult to associate blood drug concentration with cell toxicity directly, although data from the literature show the existence of such a relationship
Nausea
Vomiting
Hair loss
Diarrhea
Bronchospasm
Infection
Myelosuppression
Agranulocytosis (deficiency of granulocytes in the blood)
General discomfort
Itching
Skin exfoliation
Anemia (low number of red blood cells)
Febrile neutropenia
Angina (heart related chest pain)
ECG changes
Decreased immunity
Hypersensitivity.
Poor nutritional status.
Myelosuppression.
Serious infection.
Recent serious surgery.
Dihydropyrimidine Dehydrogenase (DPD) deficiency
Florac 250mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Florac 250mg Injection. Please consult your doctor.
Florac 250mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, esophageal, gastric, rectum, breast, biliary tract, stomach, head and neck, cervical, pancreas, renal cell, and carcinoid
myelosuppression.
dihydropyrimidine dehydrogenase deficiency.
infections.
stomatitis.
bleeding.
coronary artery disease.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Florac 250mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Florac 250mg Injection helps treat cancers of stomach, colon, rectum, breast, and lungs.
It is given as an injection into a vein, or as a drip (infusion) into a vein or artery.
The dose and the number of treatment cycles needed will depend on the type and stage of cancer that is being treated.
It may cause dizziness and visual changes. Do not drive or do anything requiring concentration until you know how it affects you.
Your doctor may regularly monitor your blood cells and liver function during treatment with this medicine.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is fluorouracil a vesicant?
No, fluorouracil is not a vesicant (irritant).
Q. Is fluorouracil safe?
Fluorouracil is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is fluorouracil a steroid?
No, flurouracil is not a steroid.
Q. Is fluorouracil cream chemotherapy?
Fluorouracil is used as chemotherapy for the treatment of cancers.
Q. Is fluorouracil cream for warts?
Yes, fluorouracil is used for the treatment of warts.
Q. Is fluorouracil the same as efudex?
Efudex is a brand name (trade name) for fluorouracil.
Q. Does fluorouracil affect normal skin?
Fluorouracil has minimal effect on the surrounding healthy skin.
Q. Does fluorouracil cause hair loss?
Yes, fluorouracil may cause temporary hair loss.
Q. Does fluorouracil cause scarring?
No, fluorouracil is not known to cause scarring.
Q. Does fluorouracil cause headaches?
Though headache is not a common side effect of fluorouracil, it may occur uncommonly is some people.
Q. Why does fluorouracil cause fatigue?
As with any chemotherapy for cancer, fluorouracil causes fatigue which is attributed to be of multi-factor origin, but inflammation and anemia are thought to be the most important factors.
