Forane Solution (250ml)

Manufacturer: Abbott

Salt Composition : Isoflurane


Forane  Solution for inhalation causes loss of consciousness which is reversible. It is administered under the supervision of a doctor or a nurse in a hospital or clinical setting. You should not self-administer this medicine.


The most common side effects include shivering, nausea, vomiting, high-grade fever, decreased blood pressure, and irregular heartbeat. Inform your doctor if you are pregnant or breastfeeding.


Also, inform your doctor if you are on any medications or have any known allergy to this medicine before the start of the procedure. It may cause an increase in intracranial pressure which is the pressure inside the skull which can affect the ability to drive. It is also advised not to operate machinery because of these effects.


Basic Information

Mechanism Of Action

Forane Solution for inhalation is put into a special anaesthetic machine (vaporiser) where it becomes a gas. Thereafter, it mixes with the oxygen that you breathe in, and induces reversible loss of consciousness. This allows surgical procedures to be carried out without pain and distress.


Pharmacokinets

Isoflurane is minimally metabolized by CYP2E1 to trifluoroacetic acid (TFA). Only approximately 0.2% of isoflurane is metabolized [Article:25593732]. Isoflurane is considered less hepatotoxic compared to halothane and enflurane but some rare incidents of fatal hepatotoxocity have been reported [Article:25593732].

Side Effects

Shivering

Vomiting

Nausea

Decreased blood pressure

High grade fever

Irregular heartbeats

Contra Indications

Hypersensitivity to isoflurane & halogenated agents.

Genetic susceptibility to malignant hyperthermia.

Patients in whom general anesthesia contraindicated.

Pregnancy Related Information

Forane Solution for inhalation may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Forane Solution for inhalation.


Breast Feeding Related Information

Forane Solution for inhalation is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

Isoflurane may be used for induction and maintenance of general anesthesia. Adequate data have not been developed to establish its application in obstetrical anesthesia.

Interactions

The metabolism of Isoflurane can be decreased when combined with Amprenavir. The risk or severity of adverse effects can be increased when Isoflurane is combined with Amyl Nitrite. The risk or severity of QTc prolongation can be increased when Isoflurane is combined with Anagrelide.

Typical Dosage

check the label for directions before use.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

Consult a doctor before taking any medicines.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

Forane Solution for inhalation is given by a vaporizer under the supervision of a doctor only.

Your doctor will monitor you regularly for blood pressure, pulse rate and heartbeat during the treatment.

Inform your doctor if you are pregnant or planning pregnancy.

How To Use

Use it as advised by your doctor or check the label for directions before use.

FAQs

Q. Is Forane Solution for inhalation a controlled substance?

No, it's not a controlled substance

Q. Is Forane Solution for inhalation carcinogenic?

No, Forane Solution for inhalation not carcinogenic.