Manufacturer: Torrent Pharmaceuticals Ltd
Salt Composition : Ketoconazole(200mg)
Fungicide Tablet should be taken in the dose and duration as prescribed by your doctor. They should be swallowed whole and taken with food. The dosage and length of treatment will depend on the condition you are being treated for. Sometimes this will be in cycles of use and non-use. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment. Tell your doctor if the infection does not get better or if it gets worse. Avoid taking antacid treatments within one hour before or two hours after you take it.
Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections. It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.
Ketoconazole is 83.7% plasma protein (mainly albumin) bound, and 15.3% is erythrocyte bound, resulting in only 1% of free drug. Animal studies indicate strong binding to the cytochrome P-450 mono-oxygenase complex. Extensive metabolism to inactive metabolites occurs, the products being mainly excreted in the faeces.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Fungicide
Nausea
Vomiting
Abdominal pain
Increased liver enzymes
Application site redness
Itching
Diarrhea
Abnormal liver function tests
Adrenal insufficiency
Application site burning
decreased function of the adrenal gland.
torsades de pointes, a type of abnormal heart rhythm.
prolonged QT interval on EKG.
abnormal EKG with QT changes from birth.
absence of stomach acid.
damage to the liver and inflammation.
abnormal liver function tests.
Fungicide Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Fungicide Tablet.
Fungicide Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
ketoconazole Tablets are indicated for the treatment of the following systemic fungal infections in patients who have failed or who are intolerant to other therapies: blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
Ketoconazole interacts with drugs such as disopyramide, dofetilide, dronedarone, methadone, pimozide, quinidine, ranolazine, among others. These interactions may increase the risk of a certain condition that affects the heart rhythm (QT prolongation).
Do not chew, crush or break it. Fungicide Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Fungicide Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Your doctor has prescribed Fungicide Tablet to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
Take it with food, preferably at the same time every day.
Do not take indigestion remedies (antacids) within two hours of taking Fungicide Tablet.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Inform your doctor if you experience an allergic reaction like skin rash, swelling of face and shortness of breath.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Fungicide Tablet is to be taken with food.
