Manufacturer: Zydus Cadila
Salt Composition : Human Normal Immunoglobulin(2.5gm)
Gammarp 2.5gm Injection has been shown to be effective in preventing infections in bone marrow transplant patients more than 20 years of age in the first 100 days post-transplant. It is used in the treatment of patients where antibody-forming capacity is severely impaired thereby subjecting them to a greater risk of infections. Gammarp 2.5gm Injection gives you antibodies that your body is not making on its own so you can fight infections. Both children and adults can have this therapy. It is administered as an injection. Your doctor will monitor you for some time after the administration of Gammarp 2.5gm Injection to check for any side effects.
Gammarp 2.5gm Injection may sometimes cause side effects like jnjection site reactions such as swelling, redness, pain, induration, itching, bruising, and rash and flushing (sense of warmth in the face, ears, neck, and trunk), . If you get any of these, or other side effects, or just feel unwell, you should tell your doctor. There may be ways of preventing or reducing these effects.
Before using it, you should tell your doctor if you have any problems with blood clotting and if you have recently had, or plan to have, a vaccination. It is not known whether this medicine is completely safe during pregnancy or breastfeeding so please take advice from your doctor.
Immune globulin belongs to class of agents called immunostimulants. It works by restoring abnormally low immunoglobulin G levels to the normal range to fight against infectious agents.
It has a distribution of IgG subclasses that is very close to that of the normal human plasma. It is therefore, used to provide passive immunisation against such diseases. Absorption: Levels usually take about 2 days to peak after SC admin.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Gammarp
Flushing (sense of warmth in the face, ears, neck and trunk)
Injection site reactions (pain, swelling, redness)
Injection site soreness
Injection site bruising
Induration (hardening of a normally soft tissue or organ)
Itching
Rash
Contraindicated in persons with isolated immunoglobulin A (IgA) deficiency. Such persons have the potential for developing antibodies to IgA and could have anaphylactic reactions to subsequent administration of blood products that contain IgA.
Gammarp 2.5gm Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Gammarp 2.5gm Injection. Please consult your doctor.
Gammarp 2.5gm Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
HUMAN NORMAL IMMUNOGLOBULIN is also used to treat inflammatory disorders such as primary immune thrombocytopenia (reduced number of platelets), Guillain-Barre syndrome (short-term inflammation of the peripheral nerves causing weakness of legs and upper limbs), Kawasaki disease (inflammation of blood vessels in children ...
HUMAN NORMAL IMMUNOGLOBULIN may interact with loop diuretics (furosemide and ethacrynic acid) and live vaccines (MMR vaccine (measles, mumps, and rubella) and varicella vaccine). Drug-Food Interactions: No interactions found.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Gammarp 2.5gm Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Gammarp 2.5gm Injection is used for the treatment of certain diseases that are caused due to lack of antibodies in your blood.
It may be injected under the skin or given into a muscle.
Your doctor will monitor you for some time after administration of Gammarp 2.5gm Injection to check for any side effects.
Do not drive or do anything requiring concentration unless you know how Gammarp 2.5gm Injection affects you.
Inform your doctor if you have received any live vaccine (e.g. oral polio, MMR) in the last three months.
Q. What should I keep in mind while taking Gammarp 2.5gm Injection?
Gammarp 2.5gm Injection can reduce the efficiency of some vaccines (like measles/mumps/rubella or chickenpox vaccines). So, inform your doctor that you are on Gammarp 2.5gm Injection before you get any vaccines. Let your doctor also know if you are pregnant, planning to get pregnant or if you are breastfeeding. Patients should be adequately hydrated before administration of<br>Gammarp 2.5gm Injection.
Q. If I feel fine, does it mean that I can discontinue my treatment with Gammarp 2.5gm Injection?
No, this only means that you are responding well to the treatment. Do not stop taking this medicine without consulting the doctor. If you stop the medication before completing the treatment then you would be putting yourself at risk as your body would no longer be able to fight infections. However, in case of doubt, you should always talk to your doctor.
Q. How long will it take for Gammarp 2.5gm Injection to start working?
Your symptoms may take 3-4 weeks to improve. This duration can vary depending on the disease you have and the way you respond to the treatment. If you are not sure, consult your doctor.
Q. Can Gammarp 2.5gm Injection cause kidney damage?
Yes, Gammarp 2.5gm Injection can cause kidney damage but not in everyone. Patients having a pre-existing kidney problem, diabetes and hypovolemia (a decrease in the volume of circulating blood) are at risk of developing kidney failure. Additionally, patients who are overweight, over 65 years of age and who are using medicines that can cause kidney damage are also at risk of developing kidney failure. Also, Gammarp 2.5gm Injection which has sucrose, fructose or maltose as an ingredient in it is more likely to cause kidney damage.
