Genexol PM 100mg (Injection)

Manufacturer: Lupin Ltd

Salt Composition : Paclitaxel(100mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

It is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Some common side effects of this medicine include nausea, vomiting, and weakness. It may also cause serious side effects such as swelling of hands, lips, hair loss, and weight gain. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function.


Basic Information

Mechanism Of Action

Genexol PM 100mg Injection is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This slows the growth of cancer cells and eventually kills them.


Pharmacokinets

Paclitaxel is a new anticancer agent showing significant promise as therapy for solid tumours and leukaemia, given alone or in combination with other chemotherapeutic agents. Paclitaxel concentrations in biological specimens can be measured using high performance liquid chromatography, or more recently by immunoassay.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Genexol PM

Nausea

Vomiting

Weakness

Low blood platelets

Rash

Upper respiratory tract infection

Urinary tract infection

Bleeding

Anemia (low number of red blood cells)

Flushing (sense of warmth in the face, ears, neck and trunk)

Hair loss

Decreased blood pressure

Peripheral neuropathy (tingling and numbness of feet and hand)

Diarrhea

Decreased white blood cell count (neutrophils)

Contra Indications

If you are suffering from any of the following diseases, you should not take Paclitaxel unless your doctor advises you to do so -

Liver Disease

Herpes

Heart Disease

Peripheral Neuropathy

Infections

Pregnancy Related Information

Genexol PM 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Genexol PM 100mg Injection.


Breast Feeding Related Information

Genexol PM 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Children Related Information

Use with caution

Below 9years: Contraindicated


Indications

Paclitaxel is a taxoid antineoplastic agent indicated as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast cancer.

Interactions

adenovirus types 4 and 7 live, oral

eluxadoline

idarubicin

idelalisib

influenza virus vaccine trivalent, adjuvanted

ivacaftor

nefazodone

palifermin

quinidine

Typical Dosage

Kindly do not self administer.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Genexol PM 100mg Injection, please consult your doctor.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Genexol PM 100mg Injection is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer, and non-small cell lung cancer.

It is given as an intravenous (IV) injection into your vein, usually over 1 hour and every three weeks.

Do not take Genexol PM 100mg Injection if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.

Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.

Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of infection.

Talk to your doctor if you have sudden weight gain or if you have swelling in your arms and legs that doesn't go away.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. Is Genexol PM 100mg Injection generic/ taxane/ FDA approved/cytotoxic?

Yes, Genexol PM 100mg Injection is generic/ taxane/ FDA approved/ cytotoxic

Q. Is Genexol PM 100mg Injection a vesicant?

Genexol PM 100mg Injection is usually a vesicant (irritant)

Q. Is Genexol PM 100mg Injection light sensitive/ hydrophobic/ cardiotoxic?

Yes, Genexol PM 100mg Injection is light sensitive/ hydrophobic/ cardiotoxic

Q. Does Genexol PM 100mg Injection cause hair loss?

Yes, Genexol PM 100mg Injection may cause hair loss as a side effect. Please inform your doctor about any side effect while you are on Genexol PM 100mg Injection therapy

Q. What is Genexol PM 100mg Injection derived from?

Genexol PM 100mg Injection is derived from bark of the Pacific yew, Taxus brevifolia.