Manufacturer: Alembic Pharmaceuticals Ltd
Salt Composition : Tamsulosin(0.4mg), Dutasteride(0.5mg)
GERIFLO D TABLET is used to treat signs and symptoms of Benign Prostatic Hyperplasia (BPH) in men. Benign Prostatic Hyperplasia (also known as enlarged prostate) is a non-cancerous growth of prostate gland, which is predominantly caused by excessive production of a stress hormone called dihydrotestosterone (DHT) in men.
Symptoms of BPH includes urinary problems such as difficulty in passing urine, urinary incontinence (unintentional passing of urine), frequent urination at night and sexual dysfunction or painful ejaculation.
During this therapy, your doctor will regularly monitor your serum prostate-specific antigen (PSA) levels to detect the incidence of prostate cancer.
Before taking GERIFLO D TABLET inform your doctor if you have any liver or kidney problems. Both pregnant women and children should avoid handling the leaking medicine, because this medicine has a high potential to get absorbed through your skin and can affect the normal development of a male baby (especially during the first 16 weeks of pregnancy).
Usage of condom during sexual intercourse is recommended among fertile men to avoid conception. GERIFLO D TABLET is not recommended for use in children and adolescents under 18 years of age. GERIFLO D TABLET should be used with caution in elderly patients above 65 years of age.
The most common side effects of taking GERIFLO D TABLET are dizziness, enlargement of breast in men and decreased sex drive. Consult your doctor if any of the side effects bothers you.
GERIFLO D TABLET reduces the symptoms of benign prostatic hyperplasia, where dutasteride works by reducing the production of a stress hormone called dihydrotestosterone and tamsulosin works by relaxing the muscles surrounding the prostate gland, thus helps in shrinkage of prostate, making it easier for the urine to pass through and relieve the symptoms.
In a small study (n=24) of two weeks duration in healthy men, dutasteride (0.5 mg daily) had no effect on the pharmacokinetics of tamsulosin or terazosin. There was also no indication of a pharmacodynamic interaction in this study. Dutasteride has no effect on the pharmacokinetics of warfarin or digoxin.
COMMON
Sexual impotence (unable to achieve or maintain an erection)
Decreased sex drive
Difficulty in ejaculation
Gynecomastia (breast enlargement or tenderness)
Dizziness
UNCOMMON
Heart failure (signs include shortness of breath, extreme tiredness and swelling in your ankles and legs)
Low blood pressure on standing
Weakness or loss of strength
Headache
Constipation, diarrhea
Nausea, vomiting
Fast heartbeat
Itchy, blocked or runny nose
Skin rash, hives, itching
Hair loss or hair growth
RARE
Swelling of the face, eyelids, lips, arms or legs
Fainting
Stop taking GERIFLO D TABLET and contact your doctor immediately if you experience any of the following side effects:
Signs of allergic reaction (such as skin rash, itching, hives, and swelling of face, eyelids, lips, arms or legs)
Stevens-johnson syndrome (a severe widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals)
Dutasteride/Tamsulosin is contraindicated in: - women and children and adolescents (see section 4.6). - patients with hypersensitivity to the active substance, other 5-alpha reductase inhibitors, soya, peanut or any of the other excipients listed in section 6.1. - patients with a history of orthostatic hypotension.
GERIFLO D TABLET is intended for use only in men. Pregnant women should not come in contact with GERIFLO D TABLET as it may cause potential abnormalities in male foetus.
Avoid consumption of alcohol while taking this medicine because it may cause excessive drowsiness. Consult your doctor before taking GERIFLO D TABLET.
GERIFLO D TABLET is intended for use only in men and therefore should not be used in breastfeeding women.
Dutasteride and tamsulosin combination is used to treat men who have symptoms of an enlarged prostate gland, which is also known as benign prostatic hyperplasia (BPH). Benign enlargement of the prostate is a problem that can occur in men as they get older. The prostate gland is located below the bladder.
Drug-Drug Interactions: DUTASTERIDE+TAMSULOSIN HYDROCHLORIDE is known to contra-indicate with medicines used to help achieve or maintain an erection (vardenafil, sildenafil citrate, tadalafil), high blood pressure (verapamil, diltiazem), anti-HIV (ritonavir, indinavir), blood thinners (warfarin), antibiotics (erythromycin), NSAIDs (diclofenac).
Drug-Food Interactions: DUTASTERIDE+TAMSULOSIN HYDROCHLORIDE is known to interact when taken along with alcohol. Also, keep your doctor informed about all the OTC medicines you are using while taking DUTASTERIDE+TAMSULOSIN HYDROCHLORIDE.
Drug-Disease Interactions: DUTASTERIDE+TAMSULOSIN HYDROCHLORIDE should not be given to the patients with eye problems (like glaucoma or cataract), liver/kidney disease, hypotension (low blood pressure).
Drug-Drug Interactions Checker List:
VARDENAFIL
SILDENAFIL
TADALAFIL
VERAPAMIL
DILTIAZEM
RITONAVIR
INDINAVIR
WARFARIN
ERYTHROMYCIN
DICLOFENAC
do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking GERIFLO D TABLET without informing your doctor.
Keep GERIFLO D TABLET out of reach of children
Store at room temperature
If you or anyone else accidentally take too much of GERIFLO D TABLET, consult your doctor immediately. Overdosage may cause acute hypotension, nausea and vomiting.
GERIFLO D TABLET is not recommended for you, if you:
Are a woman (because this medicine is for men only)
Before taking GERIFLO D TABLET, inform your doctor if you have:
An upcoming cataract surgery
Blood test for PSA (Prostate Specific Antigen)
Always take GERIFLO D TABLET as directed by your physician. Take this medicine with or without food, swallow the medicine as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking GERIFLO D TABLET without informing your doctor.
Can GERIFLO D TABLET cause prostate cancer?
This medicine can increase the risk of prostate cancer and so your doctor would regularly monitor your serum prostate specific antigen (PSA) which is used to detect prostate cancer, in order to avoid any untoward side effects.
Can GERIFLO D TABLET cause infertility?
Yes, GERIFLO D TABLET can reduce sperm count, semen volume and movement also it can cause sexual impotence, decreased sex drive or difficulty in ejaculation in men. Consult your doctor if you experience any of these side effects.
