Glysafe 500mg Tablet (10'S)

Manufacturer: Apostle Remedies

Salt Composition : Metformin(500mg)


Glysafe 500mg Tablet SR is best taken with food to avoid nausea and abdominal pain. You should take it regularly, at the same time each day, to get the most benefit. You should not stop taking this medicine unless your doctor recommends it. Your lifestyle plays a big part in controlling diabetes. Therefore, it is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Before taking this medicine, inform your doctor if you have any kidney, liver, or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.


Basic Information

Mechanism Of Action

The centre of metformin's mechanism of action is the alteration of the energy metabolism of the cell. Metformin exerts its prevailing, glucose-lowering effect by inhibiting hepatic gluconeogenesis and opposing the action of glucagon.


Pharmacokinets

Metformin is rapidly distributed following absorption and does not bind to plasma proteins. No metabolites or conjugates of metformin have been identified. The absence of liver metabolism clearly differentiates the pharmacokinetics of metformin from that of other biguanides, such as phenformin.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Glysafe

Diarrhea

Nausea

Vomiting

Flatulence

Contra Indications

Renal dysfunction.

Congestive cardiac failure needing drug treatment.

Hypersensitivity to metformin.

Acute or chronic metabolic acidosis.

Impaired hepatic function.


Pregnancy Related Information

Glysafe 500mg Tablet SR is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Glysafe 500mg Tablet SR.


Breast Feeding Related Information

Glysafe 500mg Tablet SR should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.


Indications

Metformin also has several non-FDA-approved indications, including gestational diabetes, management of antipsychotic-induced weight gain, type 2 diabetes prevention, and the treatment and prevention of polycystic ovary syndrome (PCOS). Currently, metformin is the only ADA-recommended antidiabetic for pre-diabetes.

Interactions

Iodinated contrast (used in imaging tests) Certain anticancer drugs (specifically vandetanib and drugs that fall under the class called tyrosine kinase inhibitors) Some antimicrobial drugs (such as cephalexin and rifampin) Alcohol (but only in excessive amounts)

Typical Dosage

Do not chew, crush or break it. Glysafe 500mg Tablet SR is to be taken with food.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Glysafe 500mg Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

You have been prescribed Glysafe 500mg Tablet SR to control the blood sugar level and reduce the risk of diabetic complications such as heart attacks.
Chances of weight gain and low blood sugar are lesser with this medicine as compared to other diabetes medicines.
Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Glysafe 500mg Tablet SR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Prolonged use of Glysafe 500mg Tablet SR may lead to vitamin B12 deficiency which may lead to anemia, causing fatigue, pale skin, shortness of breath or headache. Notify your doctor if you experience any of these as you may require supplements.
Your doctor will monitor your blood sugar levels and kidney functions regularly while you are taking this medication.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glysafe 500mg Tablet SR is to be taken with food.


FAQs

Q. What does Glysafe 500mg Tablet SR do exactly?

People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Glysafe 500mg Tablet SR acts in several ways to reduce the increased levels of sugar in blood. Glysafe 500mg Tablet SR decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.

Q. Does Glysafe 500mg Tablet SR cause weight loss?

Yes, Glysafe 500mg Tablet SR has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.

Q. What are the benefits of taking Glysafe 500mg Tablet SR?

Glysafe 500mg Tablet SR is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Glysafe 500mg Tablet SR when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.

Q. Can Glysafe 500mg Tablet SR make you sleepy?

Glysafe 500mg Tablet SR usually does not cause sleepiness and is well tolerated. However, the use of Glysafe 500mg Tablet SR may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Glysafe 500mg Tablet SR.