Grafalon 20mg / ml Injection



Basic Information

Pharmacokinets

Polyclonal anti-thymocyte globulin (ATG) administered before allogeneic blood hematopoietic progenitor cell transplantation reduces the risks of graft rejection and graft-versus-host disease, but may delay posttransplant immune reconstitution caused by delayed clearance of ATG from the blood.


Contra Indications

History of allergy or anaphylaxis to rabbit proteins.

Active acute or chronic infections that contraindicate any additional immunosuppression.

Indications

Treatment of acute rejection after renal transplant.

Treatment of aplastic anemia in patients.

Interactions

The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Antilymphocyte immunoglobulin (horse). The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Apremilast.