Manufacturer: Mankind Pharma Ltd
Salt Composition : Amlodipine(5mg), Metoprolol Succinate(25mg)
You can take Gudpres-AM 25 Tablet PR at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.
It may cause side effects like headache, ankle swelling, slow heart rate, and nausea. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This might raise the level of potassium in the blood, hence avoid potassium rich food or supplements. You may be asked for regular monitoring of blood pressure, kidney function, and electrolytes level while on the treatment.
Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions.
Gudpres-AM 25 Tablet PR is a combination of two medicines: Amlodipine and Metoprolol, which lowers blood pressure effectively. Amlodipine is a calcium channel blocker which works by relaxing blood vessels while metoprolol is a beta blocker that works specifically on the heart to slow down the heart rate. Together, they make the heart more efficient at pumping blood throughout the body.
Amlodipine is extensively metabolised in the liver (but there is no significant presystemic or first-pass metabolism) and is slowly cleared with a terminal elimination half-life of 40 to 50h. Volume of distribution is large (21 L/kg) and there is a high degree of protein binding (98%).Elimination is mainly by biotransformation in the liver, and the plasma half-life ranges from approximately 3 to 7 hours. Less than 5% of an oral dose of metoprolol is recovered unchanged in the urine; the rest is excreted by the kidneys as metabolites that appear to have no beta-blocking activity.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Gudpres-AM
Nausea
Slow heart rate
Abdominal pain
Dizziness
Fatigue
Sleepiness
Ankle swelling
Constipation
Edema (swelling)
Flushing (sense of warmth in the face, ears, neck and trunk)
Palpitations
Headache
Vomiting
Visual disturbance
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Breathlessness
Muscle cramp
Hypersensitivity
cardiogenic shock
decompensated cardiac failure
heart block greater than first degree
hypersensitivity
severe bradycardia
sick sinus syndrome
Gudpres-AM 25 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Gudpres-AM 25 Tablet PR.
Gudpres-AM 25 Tablet PR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
Amlodipine+Metoprolol Succinate is used in the treatment of Hypertension (high blood pressure).Amlodipine is a calcium channel blocker which works by relaxing blood vessels while metoprolol is a beta blocker that works specifically on the heart to slow down the heart rate. Together, they make the heart more efficient at pumping blood throughout the body.
CYP3A4 inhibitors
Clonidine
Cyclosporine
Fluoxetine
Itraconazole
Ketoconazole
Paroxetine
Propafenone
Quinidine
Reserpine
Gudpres-AM 25 Tablet PR may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Gudpres-AM 25 Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
It may cause dizziness. Get up slowly when rising from a sitting or lying position.
Do not stop taking the medication suddenly without talking to your doctor as it can cause sudden increase in your blood pressure.
Let your doctor know if you are pregnant or planning for pregnancy.
Use it as advised by your doctor or check the label for directions before use. Gudpres-AM 25 Tablet PR may be taken with or without food, but it is better to take it at a fixed time.
Q. Can I stop taking Gudpres-AM 25 Tablet PR if I feel well?
No, keep using Gudpres-AM 25 Tablet PR as advised by your doctor, even if you feel well. Stopping Gudpres-AM 25 Tablet PR suddenly may lead to serious complications such as heart attack and stroke.
Q. What are the instructions for the storage and disposal of Gudpres-AM 25 Tablet PR?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Can the use of Gudpres-AM 25 Tablet PR cause headache?
Yes, the use of Gudpres-AM 25 Tablet PR can cause headaches at the beginning of the treatment. Headaches usually go away after the first week of the treatment. Contact your doctor if the headaches are frequent and do not go away.
Q. What are the contraindications associated with the use of Gudpres-AM 25 Tablet PR?
Gudpres-AM 25 Tablet PR Succinate is considered to be harmful for patients who are allergic to any of its active or inactive ingredient. It should be avoided in patients with a history of asthma or lung disease. Inform your doctor about the your medical history and medicines to avoid any side effects.
Q. Can I feel dizzy after taking Gudpres-AM 25 Tablet PR?
Yes, the use of Gudpres-AM 25 Tablet PR can make you feel dizzy. This may occur when you suddenly rise up from lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
