Manufacturer: Bluemed Pharma Pvt Ltd
Salt Composition : Midodrine(2.5mg)
Gutron 2.5mg Tablet can be taken with or without food. This medicine is taken during daytime hours when people stand most often. But, it should not be taken if you are going to lie down for a long time after the dose. You should always take this medicine as advised by the doctor and should never stop it without consulting the doctor. You should monitor your blood pressure regularly while taking this medicine.
Common side effects of this medicine include headache, nausea, rash, urinatry retention, difficulty in urination, and flushing. It may also cause supine hypertension, it is increase in your blood pressure while lying down. Consult your doctor if these side effects bother you.
Before taking this medicine, it is better to let your doctor know if you are suffering from any kidney or liver disease. Also, pregnant women and breastfeeding mothers should consult doctor before taking it. You must inform doctor about all the other medicines that you are taking apart from this medicine. Your doctor may ask for monitoring of kidney and liver function before and during the treatment with this medicine.
Gutron 2.5mg Tablet is an alpha-adrenergic agonist. It works by activating specific receptors on blood vessels. This causes the blood vessels to tighten, which increases blood pressure.
Following oral administration, midodrine is rapidly absorbed and then undergoes deglycination to form desglymidodrine; peak plasma concentration of midodrine and desglymidodrine usually attained within 0.5 and 1–2 hours, respectively. Absolute bioavailability of midodrine (measured as desglymidodrine) is 93%.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Gutron
Headache
Nausea
Rash
Difficulty in urination
Supine hypertension
Urinary retention
Flushing (sense of warmth in the face, ears, neck and trunk)
Goosebumps
Midodrine hydrochloride tablets are contraindicated in patients with severe organic heart disease, acute renal disease, urinary retention, pheochromocytoma or thyrotoxicosis. Midodrine hydrochloride tablets should not be used in patients with persistent and excessive supine hypertension.
Gutron 2.5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Gutron 2.5mg Tablet. Please consult your doctor.
Gutron 2.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Midodrine is used to treat orthostatic hypotension (sudden fall in blood pressure that occurs when a person assumes a standing position). Midodrine is in a class of medications called alpha-adrenergic agonists. It works by causing blood vessels to tighten, which increases blood pressure.
Drug-drug interactions: MIDODRINE may interact with drugs used to treat depression and anxiety (e.g. duloxetine), medicines used to help control the amount of sodium and fluids in your body (e.g. fludrocortisone), and medications used to treat high blood pressure (e.g. metoprolol).
Drug-food interactions: Consuming alcohol with MIDODRINE is not advisable as it may cause unpleasant side effects.
Drug-disease interactions: MIDODRINE should be used with caution in patients with heart disease/ hypertensive effects, kidney or liver dysfunction and diabetes.
Drug-Drug Interactions Checker List:
DULOXETINE
FLUDROCORTISONE
METOPROLOL
Do not chew, crush or break it. Gutron 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 25°C
Consult a doctor before taking any medicines.
Consult a doctor before taking any medicines.
Take Gutron 2.5mg Tablet at least 4 hours before bedtime to avoid the risk of high blood pressure at night time.
Monitor your blood pressure regularly while taking this medicine.
Inform your doctor if you have a history of the prostate disorder or blood circulation problem.
Inform your doctor immediately if you notice symptoms of chest pain, palpitations, headache, shortness of breath, and blurred vision.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gutron 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Does Gutron 2.5mg Tablet raise blood pressure?
Yes, Gutron 2.5mg Tablet may cause high blood pressure when you are lying flat on your back (supine hypertension). This medicine should only be used by people whose low blood pressure affects their day-to-day life and in people who could not be treated successfully with other therapies.
Q. Does Gutron 2.5mg Tablet affect heart rate?
Gutron 2.5mg Tablet may slow down the heart rate slightly. It should be used cautiously when using it with other medicines (beta blockers, digitalis, etc.) which can further slow down the heart rate. Patients should be monitored if they experience symptoms which are suggestive of slow heart rate.
Q. Why can't I lie down after taking Gutron 2.5mg Tablet?
You should not lie down immediately after taking Gutron 2.5mg Tablet because of the risk of supine hypertension (high blood pressure which occurs when you are lying flat on your back). Therefore, it is recommended to take the last daily dose at least 4 hours before bedtime. You can reduce the risk of supine hypertension occurring during the night by elevating the head.
Q. Does Gutron 2.5mg Tablet work immediately?
Gutron 2.5mg Tablet takes about 1 hour to show its effects. However, the action lasts for a short time only, the effect persists for about 2-3 hours.
