Manufacturer: Shine Pharmaceuticals Ltd
Salt Composition : Gliclazide(40mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Gylis 40mg Tablet may be prescribed alone or along with other medicines. It should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it works.
Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.
The most common side effects of taking this medicine include indigestion and stomach upsets. It can also cause low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking, and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Some people may find that they put on weight with this medicine.
Gliclazide stimulates insulin secretion through the beta cell sulphonylurea receptor, and possibly through a direct effect on intracellular calcium transport. It specifically improves the abnormal first phase insulin release in type 2 diabetes, and also has an effect on the second phase.
A single oral dose of 40 to 120 mg of gliclazide results in a Cmax of 2.2 to 8.0 µg/ml within 2 to 8 hours. Tmax and cmax are increased after repeated gliclazide administration. Steady state concentration is achieved after 2 days administration of 40 to 120 mg of gliclazide.
Hypoglycemia (low blood glucose level)
Weight gain
Flatulence
Diarrhea
Headache
Nausea
Dizziness
have ever had an allergic reaction to gliclazide or any other medicine
have ketone bodies and sugar in your urine (diabetic ketoacidosis)
have severe kidney or liver disease
have a rare condition called porphyria
are pregnant, trying to get pregnant or breastfeeding
have a condition called G6PD-deficiency
need to have surgery
Gylis 40mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Gylis 40mg Tablet.
Gylis 40mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Second-line treatment of type 2 diabetes, in patients over 60 years: as monotherapy, when metformin is not tolerated or contra-indicated. in combination with metformin, when glycaemic control is inadequate with metformin alone.
steroid tablets, such as prednisolone
some medicines used to treat heart problems and high blood pressure
medicines to treat bacterial or fungal infections, such as clarithromycin or fluconazole
painkillers – non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or aspirin
medicines used to treat asthma, such as salbutamol
male and female hormones, such as testosterone, oestrogen or progesterone
other diabetes medicines
medicines that help to prevent blood clots, such as warfarin
Do not chew, crush or break it. Gylis 40mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Gylis 40mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
Be careful while driving or operating machinery until you know how Gylis 40mg Tablet affects you.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gylis 40mg Tablet is to be taken with food.
Q. What is the best time to take Gylis 40mg Tablet?
Take Gylis 40mg Tablet before meals or exactly as instructed by your doctor. There is evidence stating that Gylis 40mg Tablet works best at controlling post meal high blood sugar levels when taken 30 minutes before breakfast. So, if you are supposed to take it once daily, take it in the morning with breakfast with a glass of water.
Q. Is Gylis 40mg Tablet the same as metformin?
No, Gylis 40mg Tablet is not the same as metformin. Although both these oral medicines are used in the treatment of type 2 diabetes, the way they work to reduce the sugar levels are different. While Gylis 40mg Tablet acts by increasing the secretion of insulin by the pancreas, metformin acts by improving the functioning and effectiveness of the insulin already available in the body.
Q. Can you take metformin and Gylis 40mg Tablet at the same time?
Yes, Gylis 40mg Tablet and metformin can be taken at the same time but only if prescribed by the doctor. Your doctor may have prescribed taking the two together to control your uncontrolled sugar levels. However, taking the two together may cause low blood sugar which may also occur if you delay or miss a meal, exercise more than usual or take it with insulin. Follow the instructions given by your doctor strictly to avoid such complications.
Q. Is Gylis 40mg Tablet bad for kidneys?
No, Gylis 40mg Tablet is not harmful if your kidney function is normal. Any previous case of kidney problem should be informed to the doctor, so that the use of Gylis 40mg Tablet can be assessed. This is done in order to analyze whether Gylis 40mg Tablet can be given or not because it is principally excreted by the kidney. If you have kidney problems you will be started at a lower dose.
