Manufacturer: Lupin Ltd
Salt Composition : Domperidone(10mg), Ranitidine(150mg)
Helkoss D 10mg/150mg Tablet is a combination of two medicines. It is to be taken in the dose and duration advised by your doctor. In case you have missed a dose, take it as soon as you remember. Finish the full course of treatment even if you feel better. A high dose or overdose may have harmful effects on the body.
This medicine is generally well tolerated by patients. However, it may cause diarrhea, sleepiness, tiredness, headache, confusion, muscle pain in some people. Before taking the medicine always consult your doctor if you are pregnant, breastfeeding, or if you are suffering from any severe stomach, liver, kidney disease, or any known disease.
Helkoss D 10mg/150mg Tablet is a combination of two medicines: Domperidone and Ranitidine, which relieves symptoms of gastroesophageal reflux disease (GERD). Domperidone is a prokinetic which works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movement of the stomach and intestines, allowing food to move more easily through the stomach. Ranitidine is an H2 blocker (antacid). It works by reducing the amount of acid in the stomach which helps relieve acid-related indigestion and heartburn.
The DA2-receptor antagonist domperidone antagonizes the inhibitory effect of dopamine, resulting in stimulation of gastric muscle contraction. This provides a mechanism for the gastrokinetic effect of domperidone.Ranitidine Tablets is 50% absorbed after oral administration, compared to an intravenous (IV) injection with mean peak levels of 440 to 545 ng/mL occurring 2 to 3 hours after a 150 mg dose. Absorption is not significantly impaired by the administration of food or antacids.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Helkoss D
Diarrhea
Sleepiness
Tiredness
Headache
Confusion
Muscle pain
If you are suffering from any of the following diseases, you should not take Ranitidine + Domperidone unless your doctor advises you to do so -
Allergy
Liver Disease
Heart Disease
Kidney Disease
Helkoss D 10mg/150mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Helkoss D 10mg/150mg Tablet.
Helkoss D 10mg/150mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
Domperidone+Ranitidine is used in the treatment of Gastroesophageal reflux disease (Acid reflux) and Peptic ulcer disease.Domperidone is a prokinetic which works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movement of the stomach and intestines, allowing food to move more easily through the stomach. Ranitidine is an H2 blocker (antacid). It works by reducing the amount of acid in the stomach which helps relieve acid-related indigestion and heartburn.
DOMPERIDONE+RANITIDINE may have interaction with pain killers (acetaminophen, ibuprofen, aspirin, naproxen, methadone), an antidepressant (duloxetine, citalopram, escitalopram), vitamin (vitamin b12), anti-fungal (ketoconazole, fluconazole, voriconazole), antibiotics (erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine), heart-related medicines (propranolol, procainamide, amiodarone, dronedarone, quinidine, disopyramide, dofetilide, sotalol, diltiazem, verapamil), antipsychotics (haloperidol, pimozide, sertindole), gastrointestinal drugs (cisapride, dolasetron), antihistamine (mequitazine, mizolastine), anti-malarial (halofantrine), a protease inhibitor (telaprevir), anti-cancer (toremifene, vandetanib, vincamine), anti-muscarinic (diphemanil), anti-anxiety (diazepam), anticonvulsant (phenytoin), anti-asthma (theophylline), blood thinner (warfarin), antidiabetic (glipizide).
Do not chew, crush or break it. Helkoss D 10mg/150mg Tablet is to be taken empty stomach.
Store below 30°C
If you miss a dose of Helkoss D 10mg/150mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Helkoss D 10mg/150mg Tablet helps relieve acidity and heartburn.
It is a well tolerated and safe medicine with very low incidence of side effects.
It should be taken before meals as per the dose and duration prescribed by your doctor.
Avoid taking soft drinks, citrus fruits like orange and lemon while taking this medicine. These can irritate the stomach and increase acid secretion.
It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Helkoss D 10mg/150mg Tablet as it may irritate your stomach and also cause excessive drowsiness.
Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Helkoss D 10mg/150mg Tablet is to be taken empty stomach.
Q. What are the instructions for storage and disposal of Helkoss D 10mg/150mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. What is the best time to take Helkoss D 10mg/150mg Tablet?
Take Helkoss D 10mg/150mg Tablet exactly as directed by your doctor. It can be taken with or without food. To prevent heartburn and acid indigestion, take it 30-60 minutes before eating food or drinking beverages as that can lead to indigestion. Follow all directions as advised.
Q. What are the serious side effects of an overdose of Helkoss D 10mg/150mg Tablet?
Serious side effects are rare but can occur if you take a higher than the recommended dose. You could have stomach pain that seems to be getting worse (sign of an inflamed liver or pancreas), back pain, fever, pain while peeing or blood in your urine (signs of kidney problems), rash and a slow or irregular heartbeat.
Q. Can the use of Helkoss D 10mg/150mg Tablet cause dryness in mouth?
Yes, the use of Helkoss D 10mg/150mg Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry.
Q. Can I take Helkoss D 10mg/150mg Tablet if I am pregnant?
Speak with your doctor if you conceive while taking Helkoss D 10mg/150mg Tablet. Let your doctor know even if you are planning a baby. Some studies have shown that its use is unsafe during pregnancy as it may harm the fetus.
Q. Can I drink alcohol with Helkoss D 10mg/150mg Tablet?
No, alcohol is usually avoided while taking Helkoss D 10mg/150mg Tablet as it may make your stomach produce more acid than normal. This can irritate your stomach lining and make your symptoms worse.
