Manufacturer: Natco Pharma Ltd
Salt Composition : Sofosbuvir(400mg)
Hepcinat Tablet should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. It should be taken with food, preferably at a fixed time. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
It has fewer side effects as compared to other similar medicines, like fatigue, headache, nausea, insomnia (difficulty sleeping) and anemia (low red blood cell count). Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.
Hepcinat Tablet is an antiviral medication. It works by lowering a load of hepatitis C virus in the body and removing the virus from the blood over a period of time.
Pharmacokinetics. Sofosbuvir is only administered orally. The peak concentration after oral administration is 0.5–2 hours post-dose, regardless of initial dose. Peak plasma concentration of the main circulating metabolite GS-331077 occurs 2–4 hours post-dose.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Hepcinat
Fatigue
Nausea
Headache
Insomnia (difficulty in sleeping)
Anemia (low number of red blood cells)
Hypersensitivity.
Pregnancy or planning pregnancy, including men whose female partners are pregnant/planning to get pregnant.
CrCl less than 50 mL/min.
Pancreatitis.
Hemoglobinopathies (e.g., thalassemia major, sickle cell anemia)
Coadministration with diagnosing.
Hepcinat Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is not known whether it is safe to consume alcohol with Hepcinat Tablet. Please consult your doctor.
Hepcinat Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Sofosbuvir is indicated for the treatment of chronic hepatitis C infection as a component of a combination antiviral treatment regimen.
Drug-Drug Interaction: SOFOSBUVIR may interact with anticonvulsants (oxcarbazepine, carbamazepine, phenytoin, phenobarbital), wakefulness-promoting agents (modafinil), antibiotics (rifapentine, rifabutin, rifampin), anti-HIV drug (tipranavir) and medicine used to treat irregular heartbeats (amiodarone).
Drug-Food Interaction: Avoid taking SOFOSBUVIR with St. John’s wort (Hypericum perforatum) or a product containing St. John’s wort (herbal medicine used to treat depression).
Drug-Disease Interaction: If you have diabetes or liver problems other than hepatitis C (if you are awaiting liver transplantation), inform your doctor before taking SOFOSBUVIR.
Drug-Drug Interactions Checker List:
OXCARBAZEPINE
CARBAMAZEPINE
PHENYTOIN
PHENOBARBITAL
MODAFINIL
RIFABUTIN
RIFAMPICIN
TIPRANAVIR
AMIODARONE
Do not chew, crush or break it. Hepcinat Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Hepcinat Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Hepcinat Tablet is used along with other medications for the treatment of chronic hepatitis C virus (HCV) infection.
Do not skip any doses and finish the full course of treatment even if you feel better.
It has fewer side effects compared to other similar medications.
Take it with food, preferably at the same time everyday.
You will usually need to take this medicine every day for either 12 or 24 weeks.
It may cause fatigue, dizziness, and blurred vision. Don't drive or do anything requiring concentration until you know how it affects you.
Your doctor may monitor your liver function and the amount of hepatitis C virus in your body regularly.
Do not stop taking Hepcinat Tablet without your doctor’s advice.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hepcinat Tablet is to be taken with food.
Q. How does Hepcinat Tablet work?
Hepcinat Tablet.tops viral replication and thus decreases the amount of Hepatitis C virus in the body thereby resulting in less liver damage and improved liver function
Q. Is Sofosbuvir a protease inhibitor?
No. Sofosbuvir is a nucleotide polymerase inhibitor
Q. Does Hepcinat Tablet cure Hepatitis C?
Hepcinat Tablet is used to treat Hepatitis C virus infection. The treatment response with Hepcinat Tablet (in conjunction with other drugs) varies based on baseline host and viral factors.
