Manufacturer: Micro Labs Ltd
Salt Composition : Amlodipine(5mg), Lisinopril(5mg)
You can take Hipril A Tablet at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.
It may cause side effects like ankle swelling, headache, cough, weakness, and tiredness. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This might raise the level of potassium in the blood, hence avoid potassium rich food or supplements. You may be asked for regular monitoring of blood pressure, kidney function, and electrolytes level while on the treatment.
Hipril A Tablet is a combination of two medicines: Amlodipine and lisinopril which lower blood pressure effectively. It works by relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently.
Amlodipine is extensively metabolised in the liver (but there is no significant presystemic or first-pass metabolism) and is slowly cleared with a terminal elimination half-life of 40 to 50h. Volume of distribution is large (21 L/kg) and there is a high degree of protein binding (98%).The drug is not metabolized but is eliminated via the kidneys. Lisinopril probably undergoes glomerular filtration, tubular secretion, and tubular reabsorption. There is no pharmacokinetic interaction between lisinopril and furosemide.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Hipril A
Ankle swelling
Headache
Tiredness
Palpitations
Increased potassium level in blood
Sleepiness
Cough
Taste change
Flushing (sense of warmth in the face, ears, neck and trunk)
Decreased blood pressure
Upset stomach
Bilateral renal artery stenosis
Breastfeeding
Cardiogenic shock
Cerebrovascular disease
Children
Dehydrated due to sickness or diarrhea
Heart attack
Hypersensitivity
Hypertrophic cardiomyopathy
Ischemic heart disease
Hipril A Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Hipril A Tablet.
Hipril A Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
Amlodipine+Lisinopril is used in the treatment of Hypertension (high blood pressure). It works by relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently.
Aliskiren
Amiloride
Amlodipine
CYP3A4 inhibitors
Cyclosporine
Hydrochlorothiazide
Itraconazole
Ketoconazole
Olmesartan
Ritonavir
Do not chew, crush or break it. Hipril A Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Hipril A Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Hipril A Tablet for the treatment of high blood pressure.
Lowering blood pressure reduces chance of future heart attack & strokes.
It may cause dizziness. Get up slowly when rising from a sitting or lying position.
Do not take Hipril A Tablet if you are pregnant or planning for pregnancy.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hipril A Tablet may be taken with or without food, but it is better to take it at a fixed time.
