Manufacturer: Eli Lilly and Company India Pvt Ltd
Salt Composition : Insulin Lispro(100IU)
Humalog 100IU/ml Solution for Injection is normally prescribed along with a long-acting type of insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. It should be taken 15 minutes before a meal or within 20 minutes after starting a meal. Do not stop the medication unless your doctor tells you to. It is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor.
Check your blood sugar levels regularly, keep track of your results and share them with your doctor. This is very important to work out the correct dose of the medicine for you.
The most common side effect of this medicine include hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, itching, and rash. To prevent this, it is important to always inject only the correct dose of medicine, monitor your blood sugar levels regularly, and have regular meals. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include allergy at the injection site like redness, swelling, or hard lumps (lipodystrophy). Some people can also gain weight while taking insulin.
Humalog 100IU/ml Solution for Injection is fast-acting insulin which starts working within 10-20 minutes after injecting. It works similar to the insulin produced by the body. Insulin facilitates reuptake of glucose in muscle and fat cells and also blocks the release of glucose from the liver.
Insulin lispro is a rapid-acting insulin analogue used to mimic postprandial insulin spikes in diabetic individuals. The onset of action of insulin lispro is 10-15 minutes. Its activity peaks 60 minutes following subcutaneous injection and its duration of action is 4-5 hours.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Humalog
Hypoglycemia (low blood glucose level)
Weight gain
Infusion site reaction
Headache
Pain
Nasopharyngitis (inflammation of the throat and nasal passages)
Auto-antibody formation
If you are suffering from any of the following diseases, you should not take Insulin Lispro unless your doctor advises you to do so -
Kidney Disease
Liver Disease
Hypoglycemia (Low Blood Sugar)
Potassium Deficiency
Drug Allergy
Humalog 100IU/ml Solution for Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is unsafe to consume alcohol with Humalog 100IU/ml Solution for Injection.
Humalog 100IU/ml Solution for Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Use with caution
Below 9years: Contraindicated
Insulin lispro is indicated to improve glycemic control in adults and children with diabetes mellitus. Insulin is a natural hormone produced by beta cells of the pancreas. In non-diabetic individuals, a basal level of insulin is supplemented with insulin spikes following meals.
INSULIN LISPRO may have an interaction with anti-depressants (phenelzine, iproniazid, isocarboxazid, nialamide, imipramine, desipramine, tranylcypromine, moclobemide), anti-Parkinson’s drug (selegiline), antibiotic (linezolid), (lithium, tryptophan), migraines drug (sumatriptan), pain killer (tramadol), anti-ulcer (cimetidine, lansoprazole, omeprazole), anti-fungal (fluconazole), anti-stroke pills (ticlopidine), blood-thinners (warfarin, dipyridamole, and phenprocoumon), antimalarial (mefloquine), heart-related drug (flecainide, propafenone), and medicines that decrease blood levels of potassium or magnesium, as these increase the risk of life-threatening heart rhythm disorder. Besides this, the use of oral antidiabetic pills like pramlintide acetate and antibiotics (pentamidine) may cause hypoglycaemia (low blood sugar level).
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you have missed a dose of Humalog 100IU/ml Solution for Injection, your blood sugar level may become too high (hyperglycemia). Check your blood sugar and then take the next dose accordingly.
Consult a doctor before taking any medicines.
Take it 15 minutes before a meal or within 20 minutes after starting a meal.
Hypoglycemia (low blood sugar level) is a common side effect. Monitor your blood sugar level regularly.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, weakness, and anxiety.
Injection sites must be rotated to prevent hard lumps from developing at one site.
Injection below the skin of the abdomen results in faster absorption than other injection sites.
Opened vials/cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).
Do not use it if the preparation is no longer clear and colorless or if it contains particles.
Your doctor or nurse will guide you how to use this medicine.
Q. Is Humalog 100IU/ml Solution for Injection safe in pregnancy?
Yes, Humalog 100IU/ml Solution for Injection is considered safe to use in pregnancy if prescribed by your doctor. Consult your doctor if you become pregnant or are planning to become pregnant while using Humalog 100IU/ml Solution for Injection. Your dosage may need to be adjusted by your doctor and you may also require more frequent blood glucose monitoring.
Q. What are the common side effects that may be caused by Humalog 100IU/ml Solution for Injection?
The most common side effect of Humalog 100IU/ml Solution for Injection is hypoglycemia. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. Hence, regular monitoring of the blood sugar level is important. Always carry some sugary candies, glucose/glucon-D or fruit juice with you.
Q. For how long do I need to take Humalog 100IU/ml Solution for Injection?
If you are a type 1 diabetes patient, then yes, you have to take Humalog 100IU/ml Solution for Injection for the rest of your life. This is because your body is unable to produce sufficient insulin and therefore you would need Humalog 100IU/ml Solution for Injection as an external source of insulin. However, if you are a type 2 diabetes patient, in some cases your doctor may ask you to stop Humalog 100IU/ml Solution for Injection if you are able to manage your diabetes with proper exercise, diet and oral medicines.
Q. Does Humalog 100IU/ml Solution for Injection need to be refrigerated?
Unopened cartridges and unused pre-filled pens of Humalog 100IU/ml Solution for Injection must be stored in a refrigerator where the temperature is between 2°C to 8°C. Do not freeze and do not use Humalog 100IU/ml Solution for Injection if it has been frozen. When the cartridge has been inserted into the injection pen, it should not be refrigerated and should be kept at room temperature, below 86°F (30°C) and must be used within 28 days or be discarded, even if they still contain Humalog 100IU/ml Solution for Injection.
Q. Can Humalog 100IU/ml Solution for Injection cause hypoglycemia? How to prevent it?
Yes, hypoglycemia is the most common side effect of Humalog 100IU/ml Solution for Injection is hypoglycemia. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, don’t skip meals and be consistent in the timing and amount of your meals. Take some snacks as per your requirement if you over exercise. Always carry some glucose tablets, honey or fruit juice with you. Regular monitoring of the blood sugar level is important. Take all your medicines prescribed by the doctor on time and consult your doctor if you notice any fluctuations in your blood sugar levels.
Q. How do I inject the dose of my insulin?
Wash your hands before injecting. Choose a site for injection and clean the skin as instructed. Remove the pen cap and wipe the same site is not used more than once in a month. Remove the paper tab from the pen needle and then screw the needle tightly on top of the pen. Select the prescribed dose and then place the pen at around 90 degrees at the chosen injection site and press the dose button. Hold the pen in the same position for around 10 seconds to make sure the entire insulin is injected into the skin. Remove the needle, unscrew it and discard it. Place the cap on the pen and store it.
Q. Can Humalog 100IU/ml Solution for Injection be mixed with other insulin preparations?
No, Humalog 100IU/ml Solution for Injection solution must not be mixed with any other insulin preparation. Also, do not mix insulin in vials with insulin in cartridges.
Q. Where do I inject Humalog 100IU/ml Solution for Injection?
Humalog 100IU/ml Solution for Injection is injected under the skin (subcutaneously). Your doctor will show you the area of your skin where you should inject it. Try not to inject on the same spot every time. Rotate between the typical injection sites, such as abdomen, buttocks, upper legs, or upper arms. Never inject Humalog 100IU/ml Solution for Injection into a muscle or vein. Move to a new injection site every week or two. Inject in the same area of the body, making sure to move around within that area with each injection. Then move to another area of your body and repeat the process. Use the same area for at least a week to avoid extreme blood sugar variations.
Q. Is it necessary to prime my pen before using it?
Yes, you need to prime your pen before injecting. Priming means removing the air from the needle and insulin. Dial 2 units and keep the pen vertical, facing towards the ceiling. Now, press the dose button till a drop appears on the tip of the needle. If you are using the pen for the first time, you might have to repeat the process till a drop is visible.
