Manufacturer: Glaxo SmithKline Pharmaceuticals Ltd
Salt Composition : Topotecan(1mg)
Hycamtin 1mg Tablet can be taken with or without food, but better to have it at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Hycamtin 1mg Tablet is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them.
Topotecan (Hycamtin), a semisynthetic water-soluble derivative of camptothecin, is a potent inhibitor of DNA topoisomerase I in vitro and has demonstrated encouraging antitumour activity in a wide variety of tumours, including ovarian cancer and small cell lung cancer.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Hycamtin
Tiredness
Vomiting
Weakness
Nausea
Abdominal pain
Indigestion
Decreased white blood cell count
Decreased blood cells (red cells, white cells, and platelets)
Diarrhea
a bad infection
anemia
decreased blood platelets
low levels of a type of white blood cell called neutrophils
a condition where there is formation of fibrous tissue in the lung called pulmonary fibrosis
pregnancy
a patient who is producing milk and breastfeeding
lung tissue problem
radiation therapy involving the lungs
chronic kidney disease stage 3B (moderate)
chronic kidney disease stage 4 (severe)
Hycamtin 1mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consuming alcohol with Hycamtin 1mg Tablet does not cause any harmful side effects.
Hycamtin 1mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Use with caution
Below 9years: Contraindicated
Topotecan Injection is indicated for the treatment of chemotherapy-sensitive small cell lung cancer (SCLC) after failure of first-line chemotherapy. Chemotherapy-sensitive SCLC is defined as responding to first-line chemotherapy but subsequently progressing at least 60 days after chemotherapy.
infections.
bleeding disorders.
myelosuppression.
renal dysfunction.
diarrhea.
interstitial lung disease.
Do not chew, crush or break it. Hycamtin 1mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Hycamtin 1mg Tablet, please consult your doctor.
Consult a doctor before taking any medicines.
Hycamtin 1mg Tablet helps treat ovarian cancer.
Swallow it whole. Do not chew, crush or break the tablet.
It may cause diarrhea. Drink plenty of fluids and inform your doctor If you experience more than three episodes of diarrhoea per day while having treatment with this medicine.
Do not drive or operate machinery as Hycamtin 1mg Tablet may cause tiredness, drowsiness or weakness.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Your doctor may get regular blood tests done to monitor your blood cells during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hycamtin 1mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. How often is Hycamtin 1mg Tablet given?
Generally Hycamtin 1mg Tablet treatment is for 4 cycles of 21 day each, patient is given Hycamtin 1mg Tablet for first 5 days of each cycle.
Q. Does Hycamtin 1mg Tablet cause hair loss?
Yes, Hycamtin 1mg Tablet may cause temporary hair loss.
Q. Does Hycamtin 1mg Tablet cause flare reaction?
Yes, Hycamtin 1mg Tablet may cause flare reaction.
Q. How long does Hycamtin 1mg Tablet take to work?
Hycamtin 1mg Tablet may start its action once the infusion is started, however, the complete effect may be assessed only after completion of 4 cycles.
Q. Is Hycamtin 1mg Tablet a vesicant?
Hycamtin 1mg Tablet is a vesicant (irritant).
Q. Is Hycamtin 1mg Tablet effective?
Yes Hycamtin 1mg Tablet is effective if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. What is Hycamtin 1mg Tablet chemotherapy?
It is a treatment therapy that includes Hycamtin 1mg Tablet with or without combination of other drugs in treatment of cancer (Usually ovarian or lung cancer).
Q. How is Hycamtin 1mg Tablet administered?
Hycamtin 1mg Tablet is either administered orally as a capsule or as an intravenous Infusion in the arm over a period of 30 min.
