Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Imipramine(25mg)
Impramine 25mg Tablet works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose may be modified or gradually decreased before stopping the medication.
The most common side effects of this medicine include increased heart rate, blurred vision, dryness in the mouth, difficulty in urination, and constipation. Initially, this medicine may also cause a sudden drop in blood pressure, especially when you change positions. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. To lower the chances of dizziness, rise slowly if you have been sitting or lying down. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine as advised by the doctor as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should be avoided as alcohol interacts with this medicine to cause serious health issues.
Impramine 25mg Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Imipramine has a mean half life of 12 h. Its active metabolite, desipramine has a mean half life of 22.5 h 3. Imipramine has a mean clearance of 1 L/h/kg. Its active metabolite, desipramine has a mean clearance of 1.8 L/h/kg 3.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Impramine
Gastrointestinal disturbance
Nervousness
Sleep disorder
Tiredness
Imipramine is contraindicated in patients who have shown prior hypersensitivity to it and in acute porphyria, hepatic impairment and cardiovascular disease.
Impramine 25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Impramine 25mg Tablet may cause excessive drowsiness with alcohol.
Impramine 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Imipramine may be used to treat depression and nocturnal enuresis in children Label. Unlabeled indications include chronic and neuropathic pain (including diabetic neuropathy), panic disorder, attention-deficit/hyperactivity disorder (ADHD), and post-traumatic stress disorder (PTSD) 12,11,1,13,14,15,2.
Drug-Drug Interactions: IMIPRAMINE may interact with anti-depressants (fluoxetine, fluvoxamine, duloxetine, escitalopram, sertraline), antipsychotics (aripiprazole, quetiapine), anti-convulsant (carbamazepine, phenytoin, phenobarbital, pregabalin, topiramate), benzodiazepine (diazepam, nitrazepam, oxazepam, alprazolam, clonazepam), pain killer (aspirin, tramadol, codeine, dihydrocodeine), anti-HIV (ritonavir), antacid (cimetidine, esomeprazole), blood thinner (warfarin), skeletal muscle relaxant (cyclobenzaprine), anti-anxiety (alprazolam) and hormone (levothyroxine).
Drug-Food Interactions: Do not take St. John’s wort (herbal supplement to treat depression) along with IMIPRAMINE.
Drug-Disease Interactions: Inform your doctor if you have epilepsy, low blood pressure, overactive thyroid, urination problems or enlarged prostate, glaucoma, diabetes, schizophrenia, mania, pheochromocytoma (tumour of the adrenal gland), heart, kidney or liver problems.
Drug-Drug Interactions Checker List:
FLUOXETINE
FLUVOXAMINE
DULOXETINE
ESCITALOPRAM
SERTRALINE
ARIPIPRAZOLE
QUETIAPINE
CARBAMAZEPINE
PHENYTOIN
PHENOBARBITAL
PREGABALIN
TOPIRAMATE
DIAZEPAM
NITRAZEPAM
OXAZEPAM
ALPRAZOLAM
CLONAZEPAM
ASPIRIN
TRAMADOL
CODEINE
DIHYDROCODEINE
RITONAVIR
CIMETIDINE
ESOMEPRAZOLE
WARFARIN
CYCLOBENZAPRINE
LEVOTHYROXINE
Store below 30°C
If you miss a dose of Impramine 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
Consult a doctor before taking any medicines.
Impramine 25mg Tablet is used for the treatment of depression and bedwetting in children.
The main dose should be taken at night as this medicine may produce drowsiness or sleepiness.
You may be asked for regular blood tests to monitor the blood cell count or level of sodium and sugar in the blood.
Inform your doctor if you notice behavioral changes, mood changes and suicidal thoughts while taking this medicine.
Do not drive or do anything that requires concentration until you know how this medicine affects you.
Do not stop taking the medication suddenly without talking to your doctor.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Impramine 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What is Impramine 25mg Tablet used for?
Impramine 25mg Tablet is mainly used to treat depression. It is also used to treat bed wetting in children older than 6 years of age. It works by restoring the chemical imbalance in the brain, thereby enhancing mood and behavior.
Q. What are the side effects of Impramine 25mg Tablet?
Impramine 25mg Tablet may cause side effects like increased heart rate, blurred vision, dryness in mouth, difficulty in urination, constipation and orthostatic hypotension (sudden decrease in blood pressure on standing). Consult your doctor if these side effects do not go away or worry you.
Q. Can I just stop taking Impramine 25mg Tablet?
No, you must not stop taking Impramine 25mg Tablet suddenly even if you are feeling good as it may worsen your condition. Continue taking Impramine 25mg Tablet for the duration prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.
Q. Can a pregnant woman take Impramine 25mg Tablet?
No, pregnant women should avoid taking Impramine 25mg Tablet, unless recommended by the doctor. Studies have shown significant risks to the developing baby and it is given only if the benefits are clearly more than the risks involved. Taking this medicine during the last trimester of the pregnancy may cause symptoms such as breathing problems, weakness, irritability, changes in blood pressure, tremors, and spasms in the newborn. Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant or breastfeeding.
