Manufacturer: Pfizer Ltd
Salt Composition : Axitinib(5mg)
Inlyta 5mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include high blood pressure, joint pain, and loss of appetite. Diarrhea, shortness of breath, can be serious sometimes so take medicine to treat it as prescribed by the doctor or stay hydrated. Your doctor may advise for regular blood pressure checkups while you are taking this medicine. Inform your doctor if you notice a severe headache, confusion, problems with your eyesight, nausea or vomiting.
Before taking it, tell your doctor if you have thyroid problems, liver or bleeding problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by females during treatment is important to avoid pregnancy.
Inlyta 5mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
Dose increase (up to a maximum of 10 mg twice daily) or reduction is permitted based on individual tolerability. Axitinib pharmacokinetics are dose-proportional within 1-20 mg twice daily, which includes the clinical dose range.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Inlyta
High blood pressure
Joint pain
Loss of appetite
Diarrhea
Breathing problems
Abdominal pain
Constipation
Cough
Decreased appetite
Decreased level of thyroid hormones
Difficulty in speaking
Dry skin
Indigestion
Headache
Nausea
Pain in extremities
Painful blisters on hands and feet
Protein in urine
Rash
Breathlessness
Stomatitis (Inflammation of the mouth)
Taste change
Vomiting
Tell your doctor right away if you have any serious side effects, including: signs of kidney problems (such as change in the amount of urine, foamy urine), muscle/joint pain, swelling of ankles/feet/hands, unusual tiredness, shortness of breath, easy bruising or bleeding (such as nose/gum bleeds, pink/dark urine), ...
Inlyta 5mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Inlyta 5mg Tablet. Please consult your doctor.
Inlyta 5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Axitinib is used alone to treat advanced renal cell carcinoma (RCC, a type of cancer that begins in the cells of the kidneys) in people who have not been treated successfully with another medication.
Drug-Drug Interactions: AXITINIB may have interaction with strong CYP3A4/5 inhibitors (clarithromycin, diltiazem, erythromycin, itraconazole, ketoconazole, ritonavir), strong CYP3A4/5 inducers (carbamazepine, rifampicin, phenytoin, phenobarbitone, dexamethasone).
Drug-Food Interactions: Avoid alcohol consumption and smoking.
Dug-Disease Interactions: Tell your doctor if you have liver or kidney disease, heart problems, GI perforation, lung toxicity, thyroid dysfunction, or thromboembolism before starting the treatment.
Drug-Drug Interactions Checker List:
CLARITHROMYCIN
ITRACONAZOLE
KETOCONAZOLE
RITONAVIR
DILTIAZEM
CARBAMAZEPINE
PHENYTOIN
RIFAMPICIN
DEXAMETHASONE
Store below 30°C
Consult a doctor before taking any medicines.
Consult a doctor before taking any medicines.
Take it with or without food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Inlyta 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What are the possible signs and symptoms of kidney cancer?
Some possible signs and symptoms of kidney cancer include blood in the urine (hematuria) which may appear dark red, orange, or pink. As kidney cancer progresses, it may produce other symptoms such as persistent pain, pressure just below the ribs, or intense fatigue.
Q. How long should I take the Inlyta 5mg Tablet?
The duration of treatment varies from person to person. Your doctor will decide treatment duration based on your condition, response to treatment, and tolerance to side effects. Your doctor may decrease your dose or stop your treatment temporarily or permanently if you experience side effects.
Q. When should I call my doctor right away?
Get medical help right away if you have signs of allergic reaction such as rash, hives, itching, and blisters. Also, let your doctor know if you notice bleeding or blood in your cough, very high blood pressure, signs of thyroid problems such as a change in weight, nervousness, restlessness, weakness, thinning of hair after taking Inlyta 5mg Tablet. Also, if you feel sudden mood changes, fast heart rate, change in voice, fever, or chills, visit your doctor without delay.
Q. What lab tests are important before starting Inlyta 5mg Tablet?
Your doctor may advise you to undergo lab or medical tests such as blood pressure, thyroid function, kidney function, liver or pancreatic function tests, complete blood counts, urine tests, blood mineral levels including sodium or potassium before starting this medication. Women of childbearing age should have a pregnancy test before starting this medicine.
