Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Isosorbide Mononitrate(20mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Insocalm 20mg Tablet may be taken with or without food. Your doctor will decide the dose and how often you should take them. This may change from time to time depending on how well they are working. You should take this medicine as it has been prescribed and keep taking it, even if you feel well. This medicine helps to prevent chest pain in the future. If you stop taking it, your risk of chest pain will increase, especially if you stop taking them suddenly. Lifestyle changes such as diet, exercise, and not smoking may help this medication work better.
You can develop tolerance to this medicine over time, which means that the same dose becomes less effective. You have to stick to a really specific dosing schedule to prevent this from happening.
The most common side effects include headache, flushing, upper respiratory tract infection, abdominal pain, allergic reaction, chest pain, and diarrhea. If these symptoms bother you or do not go away, your doctor may suggest ways of preventing or reducing them. Some can be reduced by taking painkillers, drinking plenty of fluids, and avoiding alcohol.
Before taking this medicine tell your doctor if you have low blood pressure, increased pressure in the eye (glaucoma), kidney disease, or heart failure. Also let your doctor know if you are taking any other medicines as some may affect, or be affected by, this medicine and some may be dangerous to take with it. You should not take any medicine for erectile dysfunction with this medicine. If you are pregnant or breastfeeding, ask your doctor if this medicine is suitable. Your doctor may regularly monitor your blood pressure and heart rate during the treatment with this medicine.
Insocalm 20mg Tablet is a nitrate. It dilates peripheral arteries and veins. Dilation of the veins promotes peripheral pooling of blood and decreases venous return to the heart, thereby reducing workload of heart. As a result, the heart muscle does not need as much blood and oxygen supply.
Pharmacokinetic studies show that isosorbide mononitrate is rapidly absorbed after oral administration, reaches peak concentrations within an hour, undergoes no significant first-pass metabolism, and is virtually 100% bioavailable.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Insocalm
Headache
Flushing (sense of warmth in the face, ears, neck and trunk)
Upper respiratory tract infection
Abdominal pain
Allergic reaction
Chest pain
Diarrhea
Allergic to nitrates.
Concomitant use of isosorbide with PDE inhibitors such as sildenafil and tadalafil.
Concomitant use of isosorbide with riociguat, a soluble guanylate cyclase stimulator used for the treatment of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension[24]
Insocalm 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consuming alcohol while taking Insocalm 20mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Information regarding the use of Insocalm 20mg Tablet during breastfeeding is not available. Please consult your doctor.
Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). It does not work fast enough to relieve the pain of an angina attack that has already started.
Drug-Drug Interaction: Care should be exercised when ISOSORBIDE MONONITRATE is administered in combination with Sildenafil, tadalafil, and vardenafil used to treat male erection dysfunction, Isosorbide dinitrate which is used for angina, Blood pressure-lowering drugs like ACE inhibitors, beta-blockers (atenolol, propranolol), calcium channel blockers (nifedipine, diltiazem), angiotensin-II receptor agonists (olmesartan medoxomil, candesartan cilexetil), clonidine, diazoxide, diuretics, methyldopa, moxonidine, Dihydorergotamine used for migraine & Tricyclic antidepressants (used to treat depression).
Drug-Food Interaction: Avoid taking ISOSORBIDE MONONITRATE alongside alcohol.
Drug-Disease Interaction: People affected with liver disease low red blood cell count (Anaemia), Kidney failure (dialysis), low blood pressure (hypotension), and Increased pressure inside the eye called glaucoma should not take ISOSORBIDE MONONITRATE.
Do not chew, crush or break it. Insocalm 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Insocalm 20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Insocalm 20mg Tablet for the prevention and treatment of heart-related chest pain (angina).
Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
Insocalm 20mg Tablet may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Do not consume alcohol while taking Insocalm 20mg Tablet as it may cause increased dizziness.
It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
You may develop tolerance to Insocalm 20mg Tablet with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Insocalm 20mg Tablet as it may cause low blood pressure.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Insocalm 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Does Insocalm 20mg Tablet affect heart rate?
Yes, Insocalm 20mg Tablet may affect the heart rate. Insocalm 20mg Tablet causes a decrease in blood pressure. This decrease in blood pressure further causes a decrease in the heart rate (bradycardia). In some cases, it may also cause an increase in the heart rate (tachycardia). Consult your doctor in case you do not feel well after taking this medicine or if you notice a change in your heart rate.
Q. What if I forget to take a dose of Insocalm 20mg Tablet?
You can take the forgotten dose of Insocalm 20mg Tablet if you remember it within 12 hours. However, if you remember it after 12 hours of the scheduled time, then skip the missed dose and continue with the next dose.
Q. Can I stop taking Insocalm 20mg Tablet after sometime?
No, do not stop taking this medicine without talking to your doctor. Stopping it suddenly may increase your chances of having an anginal attack. If you have any concerns regarding Insocalm 20mg Tablet consult your doctor.
Q. What are the symptoms of an overdose of Insocalm 20mg Tablet?
Taking more than the recommended dose of Insocalm 20mg Tablet may cause throbbing headache, reddening of the skin, chills along with sweating, nausea, vomiting, and a fast heartbeat. Seek emergency help and consult your doctor immediately if you take more than the recommended dose of this medicine.
