Manufacturer: Dr Reddy's Laboratories Ltd
Salt Composition : Irinotecan(40mg)
Irnocam 40 Injection is given as an IV infusion into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include fatigue, nausea, vomiting, weakness, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Inform your doctor if you notice fever, sore throat, and continuous episodes of diarrhea. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Irnocam 40 Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them.
Irinotecan is extensively metabolized in the liver. The bipiperidinocarbonylxy group of irinotecan is first removed by a carboxyesterase to yield the corresponding carboxylic acid and SN38. This metabolite can be converted into SN38 glucuronide by UDP-glucuronyltransferase (1.1 isoform).
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Irnocam
Fatigue
Nausea
Vomiting
Weakness
Hair loss
Fever
Anemia (low number of red blood cells)
Diarrhea
Decreased white blood cell count (neutrophils)
Decreased appetite
Mucosal inflammation
Contraindications to irinotecan would involve severe allergic reactions to its group of chemotherapeutic agents, the DNA topoisomerase I inhibitors. Irinotecan is contraindicated in gastric cancer patients with peritoneal metastasis or impaired liver function.
Irnocam 40 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Irnocam 40 Injection. Please consult your doctor.
Irnocam 40 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Irinotecan is a medication used to manage and treat a variety of solid tumors. It is in the DNA topoisomerase I inhibitor class of drugs. Also known as CPT-11, irinotecan is used adjunctively with other therapeutic agents against colorectal cancer as a first- or second-line treatment.
The metabolism of Irinotecan can be increased when combined with Carbamazepine. The risk or severity of adverse effects can be increased when Irinotecan is combined with Carboplatin. The risk or severity of adverse effects can be increased when Irinotecan is combined with Carfilzomib.
Store below 30°C
If you miss a dose of Irnocam 40 Injection, please consult your doctor.\n
Consult a doctor before taking any medicines.
Irnocam 40 Injection is used in combination with other medicines for the treatment of metastatic cancer of the colon and rectum.
It is given via a drip into a vein (intravenous infusion).
It may cause dizziness and visual disturbances. Do not drive or do anything that requires mental focus until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Your doctor may get regular blood tests done to monitor your blood cells, kidney and liver function during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Inform your doctor if you notice passage of blood in stools or experience dizziness or faintness, continuous episodes of nausea, vomiting, diarrhea or fever.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
