Manufacturer: Sun Pharmaceutical Industries Ltd
Salt Composition : Sitagliptin(100mg)
Istavel 100mg Tablet is normally prescribed when diet and exercise alone or other medicines do not prove sufficient to control your blood sugar level. Your doctor may prescribe it alone or along with other diabetes medicines. It may be taken on an empty stomach or with a meal. The dose will depend on your condition, and blood sugar levels. Therefore, you should use it as advised by your doctor.
Sitagliptin increases insulin production and decreases hepatic glucose overproduction. Sitagliptin prolongs the action of GLP-1 and GIP. By enhancing active incretin levels, sitagliptin increases insulin production and lowers glucagon secretion from alpha cells, which decreases hepatic glucose overproduction
Sitagliptin was well absorbed (approximately 80% excreted unchanged in the urine) with an apparent terminal half-life ranging from 8 to 14 hours. Renal clearance of sitagliptin averaged 388 mL/min and was largely uninfluenced by the dose administered
Nasopharyngitis (inflammation of the throat and nasal passages)
Headache
Hypoglycemia (low blood glucose level)
Conjunctivitis
Cough
Vomiting
Diarrhea
Exfoliative dermatitis, history of angioedema, serious rash. ...
Type 1 diabetes mellitus. ...
Burns, fever, infection, surgery, trauma. ...
Diarrhea, gastroparesis, GI obstruction, ileus, vomiting. ...
Hypercortisolism, hyperglycemia, hyperthyroidism.
Istavel 100mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Istavel 100mg Tablet.
Istavel 100mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Sitagliptin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It is not used to treat type 1 diabetes or patients with a history of pancreatitis. It is also used in combination with metformin 8 or ertugliflozin
Sitagliptin has no known severe interactions with other drugs
Do not chew, crush or break it. Istavel 100mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Istavel 100mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Istavel 100mg Tablet should be taken at the same time every day since this helps you remember to take it.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
Be careful while driving or operating machinery until you know how Istavel 100mg Tablet affects you.
Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Istavel 100mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Does Istavel 100mg Tablet cause weight gain?
No, Istavel 100mg Tablet is not known to cause weight gain by itself. However, keeping a healthy weight is an important part of managing diabetes. Consult your doctor if you experience weight gain while taking Istavel 100mg Tablet.
Q. Is Istavel 100mg Tablet bad for your kidneys?
No, Istavel 100mg Tablet is not bad for your kidneys if your kidney function is normal. However, it is important to inform your doctor if you have, or ever had, any kidney problems. If you have kidney problems, you may need dose modification.
Q. Do I still have to manage my diet and exercise while on Istavel 100mg Tablet?
Yes, it is important to manage your diet and exercise while taking Istavel 100mg Tablet. In addition to medicine, making healthy food choices and being physically active are also important to effectively manage blood sugar levels. You may consult a dietitian and follow a diet chart that suits you best. A well-balanced diet is one part of a healthy lifestyle for people with type 2 diabetes. Additionally, thirty minutes of exercise such as a brisk walk is recommended.
Q. Can my blood sugar levels go too low on Istavel 100mg Tablet?
Yes, it is possible that your blood sugar levels may become very low (hypoglycemia). The chances are higher if you are on any other antidiabetic medicine or insulin along with Istavel 100mg Tablet. Additionally, blood sugar levels can take a huge dip if you skip meals, exercise more than usual, or if you have taken an overdose of Istavel 100mg Tablet. If you experience a sudden fall in your sugar levels, inform your doctor. The doctor may suggest dose modification to prevent your blood sugar levels from decreasing significantly (hypoglycemia). Follow your doctor’s advice and monitor your blood sugar levels regularly.
