IVMMUNE INFUSION (100ml)

Manufacturer: Biocon

Salt Composition : Human Normal Immunoglobulin


Ivmmune Infusion has been shown to be effective in preventing infections in bone marrow transplant patients more than 20 years of age in the first 100 days post-transplant. It is used in the treatment of patients where antibody-forming capacity is severely impaired thereby subjecting them to a greater risk of infections. Ivmmune Infusion gives you antibodies that your body is not making on its own so you can fight infections. Both children and adults can have this therapy. It is administered as an injection. Your doctor will monitor you for some time after the administration of Ivmmune Infusion to check for any side effects.


Ivmmune Infusion may sometimes cause side effects like jnjection site reactions such as swelling, redness, pain, induration, itching, bruising, and rash and flushing (sense of warmth in the face, ears, neck, and trunk), . If you get any of these, or other side effects, or just feel unwell, you should tell your doctor. There may be ways of preventing or reducing these effects.


Before using it, you should tell your doctor if you have any problems with blood clotting and if you have recently had, or plan to have, a vaccination. It is not known whether this medicine is completely safe during pregnancy or breastfeeding so please take advice from your doctor.


Basic Information

Mechanism Of Action

Immune globulin belongs to class of agents called immunostimulants. It works by restoring abnormally low immunoglobulin G levels to the normal range to fight against infectious agents.


Pharmacokinets

The pharmacokinetics of IGIV shows considerable intra- and interpopulation variability among patients with normal immunoglobulin levels, patients with primary immunodeficiency diseases, bone marrow transplant recipients, patients with immune deficiency due to chronic lymphocytic leukemia or multiple myeloma, very low ...


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ivmmune

Flushing (sense of warmth in the face, ears, neck and trunk)

Injection site reactions (pain, swelling, redness)

Injection site soreness

Injection site bruising

Induration (hardening of a normally soft tissue or organ)

Itching

Rash

Contra Indications

Contraindicated in persons with isolated immunoglobulin A (IgA) deficiency. Such persons have the potential for developing antibodies to IgA and could have anaphylactic reactions to subsequent administration of blood products that contain IgA.

Pregnancy Related Information

Ivmmune Infusion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Ivmmune Infusion. Please consult your doctor.


Breast Feeding Related Information

Ivmmune Infusion should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.


Indications

HUMAN NORMAL IMMUNOGLOBULIN is also used to treat inflammatory disorders such as primary immune thrombocytopenia (reduced number of platelets), Guillain-Barre syndrome (short-term inflammation of the peripheral nerves causing weakness of legs and upper limbs), Kawasaki disease (inflammation of blood vessels in children ...

Interactions

Drug-Drug Interactions: HUMAN NORMAL IMMUNOGLOBULIN may interact with loop diuretics (furosemide and ethacrynic acid) and live vaccines (MMR vaccine (measles, mumps, and rubella) and varicella vaccine).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: HUMAN NORMAL IMMUNOGLOBULIN should be used with caution in people with blood clotting disorders and immunoglobulin A (IgA) deficiency.

Drug-Drug Interactions Checker List:

FUROSEMIDE

ETHACRYNIC ACID

MMR VACCINE

VARICELLA (LIVE ATTENUATED)

Effects Of Missed Dosage

If you miss a dose of Ivmmune Infusion, please consult your doctor.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Ivmmune Infusion is used for the treatment of certain diseases that are caused due to lack of antibodies in your blood.

It may be injected under the skin or given into a muscle.

Your doctor will monitor you for some time after administration of Ivmmune Infusion to check for any side effects.

Do not drive or do anything requiring concentration unless you know how Ivmmune Infusion affects you.

Inform your doctor if you have received any live vaccine (e.g. oral polio, MMR) in the last three months.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

FAQs

Q. What should I keep in mind while taking Ivmmune Infusion?

Ivmmune Infusion can reduce the efficiency of some vaccines (like measles/mumps/rubella or chickenpox vaccines). So, inform your doctor that you are on Ivmmune Infusion before you get any vaccines. Let your doctor also know if you are pregnant, planning to get pregnant or if you are breastfeeding. Patients should be adequately hydrated before administration of<br>Ivmmune Infusion.

Q. If I feel fine, does it mean that I can discontinue my treatment with Ivmmune Infusion?

No, this only means that you are responding well to the treatment. Do not stop taking this medicine without consulting the doctor. If you stop the medication before completing the treatment then you would be putting yourself at risk as your body would no longer be able to fight infections. However, in case of doubt, you should always talk to your doctor.

Q. How long will it take for Ivmmune Infusion to start working?

Your symptoms may take 3-4 weeks to improve. This duration can vary depending on the disease you have and the way you respond to the treatment. If you are not sure, consult your doctor.

Q. Can Ivmmune Infusion cause kidney damage?

Yes, Ivmmune Infusion can cause kidney damage but not in everyone. Patients having a pre-existing kidney problem, diabetes and hypovolemia (a decrease in the volume of circulating blood) are at risk of developing kidney failure. Additionally, patients who are overweight, over 65 years of age and who are using medicines that can cause kidney damage are also at risk of developing kidney failure. Also, Ivmmune Infusion which has sucrose, fructose or maltose as an ingredient in it is more likely to cause kidney damage.