Manufacturer: Novartis India Ltd
Salt Composition : Ruxolitinib(20mg)
Jakavi 20mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Headache, dizziness, low platelet count are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, kidney and lipid levels.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Jakavi 20mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
Ruxolitinib pharmacokinetics can be described with a two-compartment model and linear elimination. Volume of distribution differs between men and women, likely related to bodyweight differences. Metabolism is mainly hepatic via CYP3A4 and can be altered by CYP3A4 inducers and inhibitors.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Jakavi
Headache
Dizziness
Low blood platelets
Anemia (low number of red blood cells)
Before using ruxolitinib, tell your doctor or pharmacist if you have a history of heart disease, stroke, cancer, or any risk factors for heart disease (such as high blood pressure, diabetes, previous blood clots, high cholesterol, smoking or history of smoking).
Jakavi 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Consuming alcohol with Jakavi 20mg Tablet does not cause any harmful side effects.
Jakavi 20mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Ruxolitinib is a medication used to manage and treat myelofibrosis, polycythemia vera, and steroid-refractory acute graft-versus-host disease. It is in the Janus Kinase inhibitor class of medications.
Alcohol (contained in alcoholic beverages) (ethanol)
Ambien (zolpidem)
Ativan (lorazepam)
Co-trimoxazole (sulfamethoxazole / trimethoprim)
Coenzyme Q10 (ubiquinone)
CoQ10 (ubiquinone)
Cosopt (dorzolamide / timolol ophthalmic)
Coumadin (warfarin)
Do not chew, crush or break it. Jakavi 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
Consult a doctor before taking any medicines.
Consult a doctor before taking any medicines.
Take it with or without food, preferably at the same time each day.
It may cause dizziness and headaches. Do not drive or do anything that requires mental focus until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Your doctor may get regular blood tests done to monitor your blood cells, liver and kidney function, and lipid levels during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Do not stop taking Jakavi 20mg Tablet without talking to your doctor first.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jakavi 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
