Manufacturer: Cadila Pharmaceuticals Ltd
Salt Composition : Carboplatin(450mg)
Karplat 450mg Infusion is given as an injection into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, fatigue, and increased liver enzyme are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice fever, sore throat, chills, unusual bleeding or bruising, and dark urine. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
You must inform your doctor if you experience allergic reactions with injection such as skin rash, itching, and trouble breathing. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Karplat 450mg Infusion is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.
Carboplatin did not bind to plasma protein in vitro but did degrade (t1/2-26 hours) to yield a reactive intermediate that bound rapidly and irreversibly to protein. The long terminal elimination half-life of plasma platinum was associated with irreversible binding of a platinum metabonate to plasma protein.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Karplat
Nausea
Vomiting
Anemia (low number of red blood cells)
Fatigue
Low blood platelets
Increased liver enzymes
Decreased white blood cell count (neutrophils)
Stomatitis (Inflammation of the mouth)
Peripheral neuropathy (tingling and numbness of feet and hand)
Diarrhea
Carboplatin Injection is contraindicated in patients with a history of severe allergic reactions to cisplatin or other platinum-containing compounds. Carboplatin Injection should not be employed in patients with severe bone marrow depression or significant bleeding.
Karplat 450mg Infusion is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Karplat 450mg Infusion. Please consult your doctor.
Karplat 450mg Infusion is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Use with caution
Below 9years: Contraindicated
Carboplatin is indicated in combination with an established combination of chemotherapeutic agents for the initial treatment of advanced ovarian carcinoma. Carboplatin is also indicated for the palliative treatment of ovarian carcinoma, recurrent after prior chemotherapy.
adenovirus types 4 and 7 live, oral.
amphotericin B deoxycholate.
bacitracin.
cidofovir.
influenza virus vaccine trivalent, adjuvanted.
palifermin.
tofacitinib.
Kindly do not self-administer.
Store below 30°C
If you miss a dose of Karplat 450mg Infusion, please consult your doctor.
Consult a doctor before taking any medicines.
It is given as an injection into the veins under the supervision of a doctor.
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
Q. Is Karplat 450mg Infusion cell cycle specific?
No, Karplat 450mg Infusion is not a cell cycle specific anticancer medication
Q. Is Karplat 450mg Infusion FDA approved?
Yes Karplat 450mg Infusion is an FDA approved drug
Q. Is it a platinum based drug?
Yes carboplatin is a platinum based drug and is effectively used in combination with other drug
Q. Does Karplat 450mg Infusion cause neuropathy/ hearing loss/ hair loss/ weight gain/ constipation/ leukemia?
Yes Karplat 450mg Infusion is known to cause side effects like neuropathy, hearing loss, hair loss, weight gain, and constipation. Please inform your doctor about any side-effect that you may observe on taking this drug. Infertility while on therapy may be caused as a side effect of this drug but it may be reverse after stopping the therapy. Yes Karplat 450mg Infusion may cause leukemia if it is used for a long duration.
Q. Is Karplat 450mg Infusion a generic?
Yes, Karplat 450mg Infusion is a generic platinum-based compound
Q. Is Karplat 450mg Infusion vesicant/cardio-toxic/ anthracycline?
No Karplat 450mg Infusion is not cardio-toxic/ anthracycline/vesicant
Q. Is Karplat 450mg Infusion used for breast cancer?
It is used to treat advanced stage breast cancer
Q. Is Karplat 450mg Infusion available in pill form?
No Karplat 450mg Infusion is not available in pill form
