Manufacturer: Cadila Pharmaceuticals Ltd
Salt Composition : Oxaliplatin(50mg)
Kinaplat 50mg Injection is given as an injection into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, fatigue, vomiting, and diarrhea are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It may cause some serious allergic reaction, inform your doctor if you notice sore lips or mouth ulcers, rash, itching and difficulty breathing. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It makes men infertile, hence men should take doctor advice about the freezing of sperm before the treatment. You must avoid driving after taking this medicine as it may cause dizziness.
Kinaplat Injection undergoes changes inside the body and interacts with DNA (genetic material). It causes certain changes in the DNA, resulting in problems in DNA synthesis leading to anti-cancer effects.
The pharmacokinetics of oxaliplatin are described by a 3-compartment model. The drug rapidly crosses the cellular membrane as a result of its lipophilicity. Hence, at the end of a 2-hour infusion, approximately 40% of the blood platinum is found in erythrocytes.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Oxiplat
Nausea
Fatigue
Anemia (low number of red blood cells)
Vomiting
Diarrhea
Decreased white blood cell count (neutrophils)
Low blood platelets
Increased liver enzymes
Peripheral neuropathy (tingling and numbness of feet and hand)
Stomatitis (Inflammation of the mouth)
Platinum hypersensitivity anaphylaxis
Posterior reversible encephalopathy syndrome
Grade 3 or 4 peripheral sensory neuropathy
Severe renal impairment
Chronic lung disease
Rhabdomyolysis
Sepsis[38]
Pregnant or intending to get pregnant
Breastfeeding
Kinaplat 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Kinaplat 50mg Injection. Please consult your doctor.
Kinaplat 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Oxaliplatin is a medication used to manage and treat metastatic colorectal cancer. It is a member of the platinum-based chemotherapeutic class of drugs and is indicated in the adjunctive treatment of stage III colorectal cancer after resection of the primary tumor and for the treatment of metastatic colorectal cancer.
adenovirus types 4 and 7 live, oral
BCG vaccine live
influenza virus vaccine quadrivalent, intranasal
measles (rubeola) vaccine
measles mumps and rubella vaccine, live
measles, mumps, rubella, and varicella vaccine, live
pimozide
rotavirus oral vaccine, live
rubella vaccine
smallpox (vaccinia) vaccine, live
typhoid polysaccharide vaccine
typhoid vaccine live
varicella virus vaccine live
yellow fever vaccine
zoster vaccine live
Kindly do not self administer.
Store below 30°C
If you miss a dose of Kinaplat 50mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Kinaplat 50mg Injection is given as an injection into veins under the supervision of a doctor.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
