Kligmel Cream (15gm)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Kligmel Cream should be used in the dose and duration as advised by your doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. It is for external use only.

Do not use this medicine more than the recommended dose. Inform your doctor if you have known allergies from this medicine. The common side effects of this medicine include burning, irritation, itchiness, and redness at the application site.

If these side effects or any other symptoms which you think are because of this medicine persist for a longer duration, please consult your doctor. Inform your doctor if you are pregnant or are suffering from any other disease. This medicine is not safe to use in breastfeeding mothers.


Basic Information

Mechanism Of Action

Hydroquinone inhibits an enzyme known as tyrosinase, which is responsible for the production of a pigment called melanin. Melanin is responsible for skin pigmentation and melasma.Tretinoin is a metabolite of vitamin A. It is responsible for the elimination of melanin that has been formed. It also has anti-inflammatory properties.Mometasone is a corticosteroid and it works by blocking the production of inflammatory chemicals like prostaglandins and leukotrienes. Mometasone narrows and constricts blood vessels, which are dilated (widened) and leaky and allowing other inflammatory cells into the skin to promote the inflammatory response.

Pharmacokinets

Hydroquinone is absorbed through the skin and metabolized primarily to sulfate and glucuronide conjugates, which are excreted in the urine. Additional metabolites include benzoquinone, multiple glutathione conjugates, and N-acetyl cysteine conjugates.Mometasone is a Corticosteroid. The mechanism of action of mometasone is as a Corticosteroid Hormone Receptor Agonist, and Corticosteroid Hormone Receptor Agonist.Tretinoin promotes cornified cell detachment and enhances shedding. Tretinoin increases mitotic activity, thereby increasing loosely-adherent corneocytes turnover. By doing so, the comedo contents can be expelled, with a reduction of microcomedo precursor lesion of acne vulgaris.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Kligmel

Application site reactions (burning, irritation, itching and redness)

Contra Indications

If you are suffering from any of the following diseases, you should not take Hydroquinone + Mometasone + Tretinoin Cream unless your doctor advises you to do so -

Eczema

Psoriasis

Asthma

Skin Disorders and Diseases

Diabetes

Liver Disease

Glaucoma

Tuberculosis (TB)

Osteoporosis

Infections

Bronchitis

Drug Allergy

Allergy

Liver Disease

Eczema

Pregnancy Related Information

Kligmel Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

No interaction found/established

Breast Feeding Related Information

Kligmel Cream is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

Hydroquinone + Mometasone + Tretinoin is used for the short-term treatment of mild to moderate melasma. It helps reduce scars, marks, blemishes, and dark circles under the eyes. It should always be used along with sun-avoidance measures, like using sunscreens and wearing protective clothing.

Interactions

HYDROQUINONE+MOMETASONE+TRETINOIN may interact with photosensitizing agents (aminolevulinic acid, porfirmer, verteporfin), topical antibiotics (benzoyl peroxide), retinoids (isotretinoin), psoralens (methoxsalen), sensitizer (methyl aminolevulinate), antiseptic (resorcinol), keratolytic agents (salicylic acid, sulfur).

Typical Dosage

Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

If you miss a dose of Kligmel Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Kligmel Cream is used for the short-term treatment of mild to moderate melasma.

It helps reduce scars, marks, blemishes, and dark circles under the eyes.

It should always be used along with sun-avoidance measures, like using sunscreens and wearing protective clothing.

Apply and massage gently till the cream is fully absorbed, once daily at night.

Initial improvement may be seen in just 2 weeks, full results generally appear after 2-3 months of regular use.

Do not apply on broken or infected areas of skin. Discontinue use if you experience irritation or allergy and consult your doctor.

Do not use it for longer than 6-8 weeks without consulting your doctor.

How To Use

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

FAQs

Q. What are the instructions for the storage and disposal of Kligmel Cream?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. How to use Kligmel Cream?

Follow the directions given by the doctor. Apply the medicine thinly and in sufficient quantity to cover the affected areas. Kligmel Cream is usually applied two or three times a day to the affected areas of skin.

Q. Will Kligmel Cream be more effective if taken more than prescribed?

No, Kligmel Cream will not be more effective if overused. Overusing the medicine can result in too much medicine being absorbed into the body. This may lead to thinning or weakening of the skin and other serious side effects. If you are experiencing increased severity of your symptoms, please consult your doctor for re-evaluation.