Kozole 150mg Tablet (1'S)

Manufacturer: Brawn Laboratories Ltd

Salt Composition : Fluconazole(150mg)

₹14.00

Strip of 1 Tablet

(Inclusive of all taxes)


Kozole Tablet is an antifungal medicine used to treat various fungal infections. It is also used to prevent the occurrence of fungal infections in cancer patients. It contains fluconazole as its active ingredient. Patients with liver and heart disorder should discuss their condition before taking this medicine. This medicine should not be used by pregnant women.


Basic Information

Mechanism Of Action

Fluconazole interacts with 14-demethylase, a cytochrome P-450 enzyme responsible for catalyzing the conversion of lanosterol to ergosterol. [4] As ergosterol forms a critical part of the fungal cell membrane, fluconazole inhibits the synthesis of ergosterol to increase cellular permeability.

Pharmacokinets

The pharmacokinetics of fluconazole are similar following intravenous and oral dosing. Oral bioavailability is greater than 90%, and concentrations peak approximately 2 hours after dosing. The apparent volume of distribution is 0.7 L/kg, and plasma protein binding is low (12%).


Side Effects

Headache

Dizziness

Diarrhea

Nausea

Stomach pain

Impaired taste

Contra Indications

low amount of magnesium in the blood.

low amount of potassium in the blood.

torsades de pointes, a type of abnormal heart rhythm.

prolonged QT interval on EKG.

abnormal EKG with QT changes from birth.

abnormal liver function tests.

pregnancy.

chronic kidney disease stage 3A (moderate)


Pregnancy Related Information

Kozole Tablet should not be used during pregnancy as it may unsafe and cause harm to the unborn baby. Inform your doctor if you are pregnant or think you may be pregnant.


Product And Alcohol Interaction

No information is available on interactions of this medicine when taken with alcohol. However, it may be best to hold off on drinking alcohol until you have finished treatment.


Breast Feeding Related Information

Fluconazole passes into human milk. Breastfeeding can be continued after a single dose; however, if you are taking this medicine repeatedly or in high doses, breastfeeding is not recommended. Caution is advised to nursing mother while giving Kozole Tablet.

Indications

Fluconazole is an antifungal medicine. It's used to treat infections caused by different kinds of fungus. The most common cause of fungal infections is a yeast called candida.

Interactions

Alfuzosin.

Amiodarone.

Aripiprazole.

Aripiprazole Lauroxil.

Artemether.

Atazanavir.

Bedaquiline.

Bepridil.


Typical Dosage

Do not chew, crush or break it. Kozole 150mg Tab is to be taken with food.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you missed any dose of Kozole Tablet, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of medicine to compensate for the missed one.


Effects Of Overdose

Symptoms of overdose of Kozole Tablet may include feeling or seeing things that are not real (hallucination and paranoid behaviour). Seek urgent medical help in case of overdose.


Expert Advice

Certain medicines can interfere with the action of Kozole Tablet or Kozole Tablet itself can affect the action of other medicines taken at the same time.

Always inform your doctor about all the medicine you are taking, that includes all prescribed or non-prescribed herbal medicines, dietary supplements as well as other treatment if you are taking for any disorder.

Certain medicines like terfenadine, voriconazole, clarithromycin, erythromycin, ranolazine, lomitapide, donepezil, pimozide and quinidine should never be taken with Kozole Tablet. As, these medicines ...

In particular, if you are taking medicines for diabetes, blood pressure, tuberculosis, brain-related disorders, bacterial infections, heart-related problem etc.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kozole 150mg Tab  is to be taken with food.


FAQs

Q: What precautions should I take when using Kozole Tablet?

Tell your doctor if you are sexually active and discuss effective contraception methods

This medicine can make your oral contraceptive pills work less efficiently

Hence if you are on this medication, then use barrier methods of contraception like condoms

Q: I have cough, cold, flu, can I take Kozole Tablet?

A: No, flu mostly occurs due to viruses. This medicine works against fungus and not viruses. Take it only if prescribed by your doctor for the complete duration of treatment.

Q: Can I take the Kozole Tablet daily?

A: Your doctor will decide the duration and frequency of this medicine after accessing your condition. Do not take this medicine on your own or for a longer duration than that prescribed.

Q: IsKozole Tablet an antibiotic?

A: No, Kozole Tablet is not an antibiotic, it is an anti-fungal medicine.

Q: I feel my condition is recovering, can I stop taking the Kozole Tablet on my own?

A: No, you should never stop taking Kozole Tablet until it is advised by the doctor, even if you are feeling good. If you stop taking this medicine, it may lead to treatment failure, recurrence of infection and may produce side effects as well.