Kryxana 200mg Tablet (21'S)

Manufacturer: Novartis India Ltd

Salt Composition : Ribociclib(200mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Kryxana 200mg Tablet may be taken with or without food and usually taken in combination with another medicine. The duration of treatment varies on the basis of your need and response to treatment. Take it in the exact dose and duration prescribed by your doctor. You may be asked for regular blood tests while taking this medication.


Common side effects of this medicine include decreased white blood cell count, nausea, fatigue, diarrhea, hair loss, vomiting, constipation, headache, and back pain. Neutropenia is a well-recognized adverse effect, in which the number of your white blood cells get reduced and your immune system gets weakened. As a result, you may be at greater risk of getting an infection. However, this side effect disappears rapidly once you stop taking the medicine.


Before using this medicine, let your doctor know if you have any preexisting medical conditions. Let your doctor also know about all the medications you are taking. Additionally, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.


Basic Information

Mechanism Of Action

Kryxana 200mg Tablet is an anti-cancer medication. It works by blocking proteins (kinases) which are important for the growth and division of cells. This slows the growth of cancer cells and eventually kills them.

Pharmacokinets

Ribociclib is approved in combination with endocrine therapy as initial endocrine-based therapy for HR-positive and HER2-negative advanced breast cancer. Ribociclib is primarily metabolized by CYP3A4 and, in vitro, is an inhibitor of CYP3A and CYP1A2.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Kryxana

Decreased white blood cell count

Nausea

Fatigue

Diarrhea

Hair loss

Vomiting

Constipation

Headache

Back pain

Contra Indications

ribociclib will increase the level or effect of naloxegol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. ribociclib increases toxicity of posaconazole by QTc interval.

Pregnancy Related Information

Kryxana 200mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Kryxana 200mg Tablet. Please consult your doctor.

Breast Feeding Related Information

Kryxana 200mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Indications

indicated for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in combination with: an aromatase inhibitor as initial endocrine-based therapy; or.

Interactions

The metabolism of Ribociclib can be decreased when combined with Ciprofloxacin. The metabolism of Cisapride can be decreased when combined with Ribociclib. The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Citalopram.

Typical Dosage

 Do not chew, crush or break it. Kryxana 200mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

Consult a doctor before taking any medicines.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

If you forget to take the medicine or vomit, skip the missed dose and follow a regular schedule. Do not take a double dose to make up missed dose

Use effective contraception method to prevent pregnancy while taking this medicine.

It may cause dizziness. Avoid driving or any activity requiring mental focus until you know how it affects you.

You may be asked for regular blood tests while taking this medication. Inform your doctor if you notice symptoms of infection like fever, chills, and weakness.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Do not stop taking the medication without talking to your doctor first.

Take it with or without food, preferably at the same time every day, to avoid missing a dose.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kryxana 200mg Tablet may be taken with or without food, but it is better to take it at a fixed time.