Manufacturer: Roche Products India Pvt Ltd
Salt Composition : Mefloquine(250mg)
Larium 250mg Tablet should be used in the dose and duration as advised by your doctor. Take it with food to decrease the risk of stomach upset. Do not skip any doses and finish the full course of treatment even if you feel better.
Some people may have stomach pain, abnormal dreams, chills, depression, and diarrhea, as side effects of this medicine. Please consult your doctor if these side effects persist for a longer duration. Inform your doctor if you ever had fits (seizures) or any problems with your kidney, heart, or liver.
Larium 250mg Tablet is an antiparasitic medication which treats malaria. It works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.
These have shown in healthy volunteers that mefloquine is absorbed with a half-life of 1 to 4 hours and a time to peak concentration of 7 to 24 hours (median 16.7 hours).
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Larium
Abdominal pain
Abnormal dreams
Anxiety
Chills
Depression
Diarrhea
Dizziness
Fever
Headache
Atrial arrhythmias (altered heart rate)
Insomnia (difficulty in sleeping)
Itching
Loss of appetite
Muscle pain
Nausea
Rash
Ringing in ear
Vertigo
Visual impairment
Vomiting
Fatigue
Mefloquine should not be prescribed for prophylaxis in patients with active depression, a recent history of depression, generalized anxiety disorder, psychosis, schizophrenia or other major psychiatric disorders, or with a history of convulsions.
Larium 250mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Larium 250mg Tablet. Please consult your doctor.
Larium 250mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Mefloquine is indicated for the treatment of mild to moderate cases of malaria caused by Plasmodium falciparum and Plasmodium vivax. It is effective against chloroquine-resistant forms of Plasmodium falciparum.
Drug-Drug Interaction: MEFLOQUINE may interact with other antimalarial medicines (chloroquine, quinidine, quinine), antidepressants (amitriptyline), antipsychotics (phenothiazine), medicines for fits/epilepsy (carbamazepine, phenytoin, phenobarbital, valproate), antifungal (ketoconazole), antibiotics (rifampicin, penicillins, cephalosporins), medicines for HIV infections (efavirenz), painkiller (tramadol), blood thinner (warfarin).
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: If you have depression, heart disease, fits/ epilepsy and liver disease, inform your doctor before taking MEFLOQUINE.
Drug-Drug Interactions Checker List:
CHLOROQUINE
QUINIDINE
QUININE
AMITRIPTYLINE
PHENOTHIAZINE
CARBAMAZEPINE
PHENYTOIN
PHENOBARBITAL
VALPROATE
RIFAMPICIN
PENICILLIN
KETOCONAZOLE
EFAVIRENZ
TRAMADOL
WARFARIN
Do not chew, crush or break it. Larium 250mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Larium 250mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Larium 250mg Tablet should be taken with food to prevent a stomach upset.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Tips to reduce the chance of being bitten by mosquitoes:
Wear light-colored and covered clothing when you are outside after sunset.
Use insect repellent creams or sprays on parts of your body not covered by clothing.
Spray to kill any mosquitoes that may have entered rooms in spite of screening.
It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Inform your doctor if you have kidney liver or heart disease.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Larium 250mg Tablet is to be taken with food.
Q. Who should not use Larium 250mg Tablet?
Use of Larium 250mg Tablet should be avoided in patients who are allergic to Larium 250mg Tablet or any of its components. However, if you are not aware of any allergy or if you are using Larium 250mg Tablet for the first time, consult your doctor.
Q. What should I tell my doctor before starting treatment with Larium 250mg Tablet?
Before starting treatment with Larium 250mg Tablet, inform your doctor if you have any other health conditions like kidney- or heart-related problems. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Also, let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are pregnant or breastfeeding.
Q. Is Larium 250mg Tablet safe?
Larium 250mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Q. What if I forget to take a dose of Larium 250mg Tablet?
If you forget a dose of Larium 250mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
