Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Lenalidomide(10mg)
Lenome 10 Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include headache, weakness, nausea, rash, and dizziness amongst others. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Hence, take caution while performing the activity that might increase your chances of bleeding or avoid contact with people suffering from an infection such as a cold. Regular blood tests are required to check your blood cells while on treatment.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You are advised to drink plenty of fluids to stay hydrated while taking this medicine.
Lenome 10 Capsule is an anti-cancer medication. It works by enhancing the immune system that indirectly attacks the cancer cells. It prevents the growth of new blood vessels within the tumor. It also restricts the production of chemical messengers (cytokine and growth factor) which are responsible for the growth of cancer cells. This is how it works against cancer.
Approximately 82 % of an oral dose is excreted as lenalidomide in urine within 24 h. Lenalidomide has a short half-life (3–4 h) and does not accumulate in plasma upon repeated dosing. Its pharmacokinetics are consistent across patient populations, regardless of the type of hematologic malignancy.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lenome
Headache
Nausea
Rash
Breathlessness
Dizziness
Fatigue
Decreased white blood cell count (neutrophils)
Joint pain
Itching
Diarrhea
Low blood platelets
Peripheral edema
Cough
Back pain
Upper respiratory tract infection
Decreased appetite
Nasopharyngitis (inflammation of the throat and nasal passages)
contraindicated in patients who have demonstrated hypersensitivity (e.g., angioedema, Stevens-Johnson syndrome, toxic epidermal necrolysis) to lenalidomide
Lenome 10 Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
It is not known whether it is safe to consume alcohol with Lenome 10 Capsule. Please consult your doctor.
Lenome 10 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Lenalidomide is indicated for the treatment of adult patients with multiple myeloma (MM) in combination with dexamethasone. It is also indicated as maintenance therapy in multiple myeloma following autologous hematopoietic stem cell transplantation (auto-HSCT).
Drug-Drug Interactions: LENALIDOMIDE may interact with digitalis glycosides (digoxin), blood thinner (warfarin), and hormone (erythropoietin).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have anaemia, blood clots, infections, heart, kidney, or liver problems.
Drug-Drug Interactions Checker List:
DIGOXIN
WARFARIN
ERYTHROPOIETIN
Lenome 10 Capsule may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Lenome 10 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You may be monitored with regular blood tests before and during the treatment as lenalidomide may cause a fall in the white blood cells and platelets, required to fight infection, Hemoglobin and blood clotting.
Avoid activities that may cause bruising or injury and avoid contact with people who have colds or infections.
It makes your skin sensitive towards sunlight. Apply sunscreen or wear protective while going out.
It may cause dehydration. Drink plenty of water to stay hydrated while taking medication.
It is not recommended for use in children and adolescents under 18 years.
You should use proper contraceptive methods at least 4 weeks before, during and until 4 weeks after stopping treatment.
Woman of childbearing potential will be required to undergo pregnancy tests before and after the treatment.
You should inform your doctor or dentist that you are taking Lenome 10 Capsule before you receive any medical or dental care, emergency care, or surgery.
It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
You may be at risk of developing acute myelogenous leukemia, fatal liver problems, severe skin reactions, and fatal heart problems during treatment with Lenome 10 Capsule. You should discuss in advance the benefits and risks of taking this medicine.
Take this medicine in the dose and duration as advised by your doctor. Lenome 10 Capsule may be taken with or without food, but it is better to take it at a fixed time.
Q. Can I take Lenome 10 Capsule empty stomach?
Lenome 10 Capsule may be taken with or without food. Always take it exactly as prescribed by your doctor. Do not crush, cut or chew the capsules. Swallow it whole with water. You should take Lenome 10 Capsule at about the same time on the scheduled days.
Q. Can Lenome 10 Capsule be given to patients who are on dialysis?
Yes, Lenome 10 Capsule is given to dialysis patients after the dialysis is done. However, the doctor may adjust the dose if needed in patients undergoing.
Q. What are the side effects of Lenome 10 Capsule?
Lenome 10 Capsule may cause side effects which include diarrhea, constipation, stomach pain, loss of appetite, weight loss, weakness, dizziness, change in ability to taste, and pain or burning of the tongue, mouth, or throat. The medicine may also cause decreased sense of touch, burning or tingling in the hands or feet, difficulty falling asleep or staying asleep, depression, and joint, muscle, bone, or back pain. You may also experience sweating, dry skin, abnormal hair growth in women, uncontrollable shaking of a part of the body, decrease in sexual desire or ability or painful, frequent, or urgent urination. Tell your doctor if any of these symptoms are severe or do not go away.
Q. Can Lenome 10 Capsule cause cancer?
People with multiple myeloma (a form of cancer that begins in plasma cells, a type of white blood cell) who receive melphalan (chemotherapy) and a blood stem cell transplant with the addition of Lenome 10 Capsule have a higher risk of developing new cancers. These types of cancers may include certain blood cancers (acute myelogenous leukemia or AML) and a type of lymphoma called Hodgkin lymphoma. Talk to your doctor about your risk of developing new cancers if you are taking Lenome 10 Capsule.
