Leoquin R Tablet (2'S)

Manufacturer: Leo Pharmaceuticals

Salt Composition : Chloroquine

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Leoquin R Tablet should be used in the dose and duration as advised by your doctor. Take it with food to decrease the risk of stomach upset. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned. Take measures to reduce the chance of being bitten by mosquitoes like using insect repellent creams on parts of your body, not covered by clothing. Spray mosquito repellent to kill any mosquitoes that may have entered rooms in spite of screening. Wear light-colored and covered clothing when you are outside after sunset.

Some people may experience rash, headache, dizziness, and vomiting as side effects of this medicine. It may also cause stomach pain, diarrhea, loss of appetite, and nausea. Please consult your doctor if these side effects persist for a longer duration.

Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. It may cause blurring of vision. Therefore, regular eye examinations are recommended while on treatment with this medicine. When used long-term, your doctor may monitor the amounts of the different types of blood cells in your blood regularly. Inform your doctor if you have unexplained bruising or bleeding, sore throat, fever, or a general feeling of tiredness.


Basic Information

Mechanism Of Action

The drug chloroquine is bactericidal for Bacillus megaterium; it inhibits DNA and RNA biosynthesis and produces rapid degradation of ribosomes and dissimilation of ribosomal RNA. Inhibition of protein synthesis is also observed, evidently as a secondary effect.

Pharmacokinets

Chloroquine is predominantly eliminated in the urine. 50% of a dose is recovered in the urine as unchanged chloroquine, with 10% of the dose recovered in the urine as desethylchloroquine. The half life of chloroquine is 20-60 days. Chloroquine has a total plasma clearance of 0.35-1L/h/kg.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Leoquin R

Rash

Headache

Dizziness

Vomiting

Nausea

Stomach pain

Loss of appetite

Diarrhea

Contra Indications

Chloroquine should not be used in patients with retinal or vision changes unless treating acute malaria. Chloroquine is also contraindicated in patients who suffer from a known hydroxychloroquine sensitivity.

Pregnancy Related Information

Leoquin R Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Leoquin R Tablet. Please consult your doctor.


Breast Feeding Related Information

Leoquin R Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.


Indications

Malaria (Vivax malaria)

Amoebic liver abscess.

Juvenile idiopathic arthritis (JIA)

Porphyria.

Systemic lupus erythematosus.

Discoid lupus erythematosus.

Polymorphic light eruptions.

Rheumatoid Arthritis.


Interactions

Some products that may interact with this drug are: mefloquine, penicillamine, remdesivir. Many drugs besides chloroquine may affect the heart rhythm (QT prolongation). Some examples are amiodarone, azithromycin, disopyramide, dronedarone, pimozide, quinidine, among others.

Typical Dosage

Do not chew, crush or break it. Leoquin R Tablet is to be taken with food.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

If you miss a dose of Leoquin R Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Leoquin R Tablet is used for the prevention and treatment of malaria.

Take it with food to decrease the risk of stomach upset.

Tips to reduce the chance of being bitten by mosquitoes:

Wear light-colored and covered clothing when you are outside after sunset.

Use insect repellent creams or sprays on parts of your body not covered by clothing.

Spray to kill any mosquitoes that may have entered rooms despite screening.

It may cause a blurring of vision when you first start taking it. Use caution while driving or doing anything that requires concentration.

Eye examination before and at 3–6 monthly intervals during use is required if patients are receiving Leoquin R Tablet at continuous high doses for a longer duration.

It may cause low blood sugar levels. Monitor your blood sugar level regularly, if you are diabetic.

When used long-term, your doctor may monitor the amounts of the different types of blood cells in your blood regularly. Inform your doctor if you have unexplained bruising or bleeding, sore throat, fever, or a general feeling of tiredness.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Leoquin R Tablet is to be taken with food.

FAQs

Q. What is Leoquin R Tablet and what it is used for?

Leoquin R Tablet is an anti-malarial medicine that is used for the treatment and prevention of malaria.

Q. How long does it take for malaria symptoms to show?

Symptoms of malaria can develop as quickly as 7 days after you are bitten by an infected mosquito. Usually, the symptoms may take up to 7 to 18 days to appear (incubation periods) from the day of the infection. Initial symptoms of malaria are flu-like which include feeling hot and shivery, fever, muscle pains, vomiting, headaches, and diarrhea.

Q. Is it safe to use Leoquin R Tablet for a long period of time?

If your doctor has prescribed you Leoquin R Tablet for a longer period of time, you should get your eyes checked regularly. This is because chloroquine present in this medicine might cause blurred vision, difficulty reading (due to words disappearing), and a rare eye condition called retinopathy if taken for a longer period of time.

Q. Who should not use Leoquin R Tablet?

Inform your doctor if you have psoriasis before taking Leoquin R Tablet since it may make your condition worse.