Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Thyroxine(50mcg)
Bottle of 100 Tablet
(Inclusive of all taxes)
Before you start taking Lethyrox 50 Tablet, your doctor will do a blood test to see what dose you need. Once you start taking the medicine, you will have regular blood tests to see how well it is working, and the dose may be adjusted from time to time. It is best taken on an empty stomach before your first meal of the day. You should take this medicine regularly to get the maximum benefit. It may take several weeks before your symptoms start to improve. You may need to take it for the rest of your life. If you stop taking it, your symptoms are likely to come back.
The most common side effects of this medicine are caused by taking a higher dose than you need. Possible side effects include palpitations (irregular heartbeat), vomiting, anxiety, diarrhea, weight loss, nervousness, or restlessness. Most side effects will disappear once you are on the right dose. Call your doctor straight away if you have a very high temperature, fast or irregular heart rate, low blood pressure, yellowness in the eye/skin, confusion, or fits.
Lethyrox 50 Tablet may cause weight loss but should not be prescribed or taken to treat obesity. If you become pregnant while taking this medicine, inform your doctor right away as the dose may have to be increased/readjusted. Many other drugs affect the way this medicine works. Ask your doctor for advice if you are taking any other medications.
Thyroxine is released from its precursor protein thyroglobulin through proteolysis and secreted into the blood where is it then peripherally deiodinated to form triiodothyronine (T3) which exerts a broad spectrum of stimulatory effects on cell metabolism.
Levothyroxine is mainly absorbed in the small intestine, more specifically through the duodenum, jejunum and ileum. Very little is absorbed in the stomach. Consequently, patients with shorter small intestines (bowel resection) have reduced absorption and require higher levothyroxine doses.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lethyrox
Palpitations
Vomiting
Anxiety
Diarrhea
Flushing (sense of warmth in the face, ears, neck and trunk)
Weight loss
Nervousness
Restlessness
overactive thyroid gland.
diabetes.
pituitary hormone deficiency.
a condition where the adrenal glands produce less hormones called Addison's disease.
coronary artery disease.
osteoporosis, a condition of weak bones.
decreased calcification or density of bone.
Lethyrox 50 Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Consuming alcohol with Lethyrox 50 Tablet does not cause any harmful side effects.
Lethyrox 50 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Levothyroxine is used to treat an underactive thyroid (hypothyroidism). It replaces or provides more thyroid hormone, which is normally produced by the thyroid gland. Low thyroid hormone levels can occur naturally or when the thyroid gland is injured by radiation/medications or removed by surgery.
A number of drugs have been shown to impair the absorption of levothyroxine; these drugs include calcium carbonate, aluminum- containing antacids, sucralfate, iron supplements, cholestyramine, sevelamer, and, possibly, ciprofloxacin, raloxifene, and orlistat.
Do not chew, crush or break it. Lethyrox 50 Tablet is to be taken empty stomach.
Store below 30°C
If you miss a dose of Lethyrox 50 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Lethyrox 50 Tablet should be taken on an empty stomach (ideally, first thing in the morning). No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine.
It may take 6 to 8 weeks to get the full effect.
For most people, Lethyrox 50 Tablet can be a lifelong medication. Do not discontinue it without discussing your doctor.
Inform your doctor if you have diarrhea, nervousness, irritability, sleep disturbances, shaking hands, or chest pain. Your doctor may adjust your dose.
Leave a gap of at least 4 hours before taking any antacids, calcium or iron supplements, and multivitamins, as these may interfere with the effect of the medicine.
Get your hormone levels checked regularly and inform your doctor if you notice a significant change in your body weight. The dose may need to be adjusted.
Inform your doctor before changing the brand of Lethyrox 50 Tablet as all brands may not have the same effect.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lethyrox 50 Tablet is to be taken empty stomach.
Q. What should I do if I accidentally take more than the dose required?
An overdose of this medicine may cause nervousness, anxiety, rapid heartbeat, hand tremors, excessive sweating, weight loss, and sleep problems. You should immediately consult your doctor in case of an overdose.
Q. How long do I need to take Lethyrox 50 Tablet?
You should take Lethyrox 50 Tablet as long as your doctor has recommended. Usually, it is prescribed for the long term and you may have to take it lifelong. Do not stop taking the medicine, as your symptoms of low levels of thyroid hormone may reoccur.
Q. How should Lethyrox 50 Tablet be taken?
Take Lethyrox 50 Tablet exactly as advised by your doctor. Lethyrox 50 Tablet should be taken orally preferably before breakfast or as a first meal of the day. It should be swallowed whole with plenty of water.
Q. Being a diabetic what should I be aware of while taking Lethyrox 50 Tablet?
Lethyrox 50 Tablet may raise blood sugar levels and may affect the working of other anti-diabetic medicines which you might be taking. Hence, dose adjustment may be required. Consult your doctor who will help you with dose management.
