Leuprosta Depot 22.5mg Injection (1ml)

Manufacturer: Alkem Laboratories Ltd

Salt Composition : Leuprolide(22.5mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

In women, it is used for the treatment of uterine fibroids and endometriosis (a condition that causes symptoms like painful periods, excessive bleeding, pain while passing urine, etc). It is also used to treat very early puberty in children. This medicine will be given to you in a hospital or clinic by a doctor or nurse as an injection. You should avoid self-injecting. Before using Leuprosta Depot Injection, inform the doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history.


Basic Information

Mechanism Of Action

Leuprorelin in Leuprosta Depot Injection works by lowering the levels of testosterone (in men) and estrogen (in women) in the body.


Pharmacokinets

Leuprolide has a terminal elimination half-life of approximately three hours. Leuprolide administered as a 1 mg intravenous bolus in healthy males has a mean systemic clearance between 7.6 and 8.3 L/h. Leuprolide is considered extremely safe, with low dose-related toxicity and comparatively mild adverse effects.

Side Effects

Injection site reactions such as pain, redness, swelling

Tiredness

Sweating

Hot flashes

Altered mood

Joint or bone pain

Headache

Nausea

Contra Indications

If you are allergic to Leuprorelin or any other ingredients of Leuprosta Depot Injection.

If you experience abnormal or irregular vaginal bleeding, which the doctor is unaware of.

If you are pregnant, planning a pregnancy or are breastfeeding.

Pregnancy Related Information

A:Leuprosta Depot Injection must not be used during pregnancy as there is limited information available in pregnant women. If you get pregnant while on treatment, discontinue using this medicine and immediately contact your doctor. Proper birth control measures should be taken while on treatment.


Product And Alcohol Interaction

A:You should avoid consuming alcohol while on treatment with Leuprosta Depot Injection.


Breast Feeding Related Information

A:Leuprosta Depot Injection should not be used while breastfeeding as there is limited safety information available. Please consult your doctor before using this medicine.


Indications

Leuprolide is a medication used in the management and treatment of prostate cancer, endometriosis, uterine fibroids, precocious puberty, and other sex hormone-related conditions. It is in the GnRH agonist class of medications.

Interactions

Drug-Drug Interaction: LEUPROLIDE may interact with heart rhythm problems treating drugs (quinidine, procainamide, disopyramide, amiodarone, sotalol), steroids (dexamethasone, methylprednisolone) and prednisone antibiotics (moxifloxacin), opioid pain killers (methadone) and antipsychotics (citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline).

Drug-Food Interaction: No interactions found/established.

Drug-Disease Interaction: LEUPROLIDE should be used with caution in cases of liver or kidney diseases, heart diseases, recent heart attack, depression, brain tumours, electrolyte imbalance, diabetes, fits, weak bones and high cholesterol levels.

Drug-Drug Interactions Checker List:

QUINIDINE

PROCAINAMIDE

DISOPYRAMIDE

AMIODARONE

DEXAMETHASONE

METHYLPREDNISOLONE

PREDNISOLONE

MOXIFLOXACIN

METHADONE

CITALOPRAM

ESCITALOPRAM

FLUOXETINE

FLUVOXAMINE

PAROXETINE

SERTRALINE

Typical Dosage

Follow any instructions suggested by the doctor or nurse during the procedure or for aftercare.


Storage Requirements

Store Leuprosta Depot Injection under the conditions mentioned on the pack.

Keep it out of reach of children and pets.

Effects Of Missed Dosage

You will be monitored by the doctor or nurse as to when Leuprosta Depot Injection should be given to you. It is unlikely that the dose will be missed. However, if you think your doctor or nurse might have missed a dose, inform them.

Effects Of Overdose

Leuprosta Depot Injection will be given to you by a doctor or nurse. Therefore, it is less likely that you may get an overdose of this medicine. If you experience any other symptoms right after taking this injection, seek urgent medical help.

Expert Advice

You have diabetes.

You have problems with your heart, liver or kidneys.

You have or are at an increased risk of having a bone condition called osteoporosis.

You consume alcohol regularly.

You suffer from any mental health problems.

You continue to have your periods after starting Leuprosta Depot Injection.

You notice severe or abnormal vaginal bleeding.

You or your partner need to use proper birth control measures (non-hormonal contraception) while on treatment.

How To Use

Leuprosta Depot Injection will be given to you in hospital by your doctor or nurse. Do not self-inject this medicine.

Follow any instructions suggested by the doctor or nurse during the procedure or for aftercare.

FAQs

Q: What is the use of Leuprosta Depot Injection?

Leuprosta Depot Injection is used in men for the treatment of prostate cancer.

It is also used in women to treat uterine fibroids and endometriosis (causing symptoms such as menstrual cramps, excessive bleeding, pain while urinating, etc.).

This medicine is also used in children to treat early puberty.

Q: What should be discussed with my healthcare professional before I start the treatment with Leuprosta Depot Injection?

Inform the doctor about your detailed medical & surgical history.

Inform your doctor if you have heart, liver or kidney disease or have fits.

Inform your doctor if you are pregnant, breastfeeding or planning to have a baby.

Leuprosta Depot Injection may interact with other medicines, hence, inform your doctor if you are taking any other medicines including supplements or herbal products. Also, inform your doctor if you are stopping any medicine.

Q: Does Leuprosta Depot need to be refrigerated?

Store Leuprosta Depot under the conditions mentioned on the pack.

It is usually stored at room temperature, protected from moisture.

Keep it out of reach of children and pets.